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u/hugo_norgaard

Contributes reviews on supplier material. Based in Ibadan.

member · joined 14 May 2025

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Comments — page 2 of 3

comment on [Discussion] the T2D advice in here is 16 years out of date in c/t2dglp1 · 2 points · 4 months ago

no medication-stopping advice, ever

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comment on small win: SURMOUNT stopped being a problem at week 65 in c/trialwatch · 110 points · 5 months ago

genuine question, not being difficult: how do you know

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comment on goal weight is the most under-discussed thing in c/coldchain in c/maintenancephase · 24 points · 6 months ago

Regain on a taper is expected. 14% back over 28 weeks, which matches the discontinuation data. Planned for it.

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comment on goal weight is the most under-discussed thing in c/coldchain in c/maintenancephase · -27 points · 6 months ago

lowest effective dose is lowest effective dose, find it or stay higher

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comment on the hazard ratio thing finally clicked for me and I want to write it down in c/trialwatch · 86 points · 6 months ago

Strongly agree. Phase 2 is investigational, not conclusive.

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comment on goal weight: the version I wish someone had shown me in week 1 in c/maintenancephase · 13 points · 6 months ago

the plateau is where the learning happens

Counter-anecdote: opposite result, same dose. Which mostly tells us the variance is huge.

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comment on anyone else notice hypoglycaemia kicking in around week 40 in c/t2dglp1 · 5 points · 7 months ago

glycaemic control first, that is the original indication

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comment on [Discussion] the T2D advice in here is 19 years out of date in c/t2dglp1 · 9 points · 8 months ago

Slight fix: the number was 98.1, not 98.0.

Counter-anecdote: opposite result, same dose. Which mostly tells us the variance is huge.

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comment on [Results] 96 weeks on 0.25mg, full numbers, ask me anything boring in c/newbiequestions · 7 points · 8 months ago

Yeah, that is totally normal for week 15.

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comment on [Results] 96 weeks on 0.25mg, full numbers, ask me anything boring in c/newbiequestions · 34 points · 8 months ago

Respectfully this is a sample of one presented as a finding.

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comment on [PSA] glycaemic control is not what most of this community thinks it is in c/t2dglp1 · 2 points · 11 months ago

I am going to push back on this slightly.

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comment on why does nobody talk about goal weight in c/maintenancephase · 18 points · 1 year ago

the 12.5mg dose works fine for 37 weeks of the month

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comment on what would you tell week-1 you about hazard ratio in c/trialwatch · 11 points · 1 year ago

absolute risk reduction, not relative risk reduction, that is how you decide

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comment on SELECT — 9 things I got wrong before I got it right in c/trialwatch · 9 points · 1 year ago

absolute risk reduction, not relative risk reduction, that is how you decide

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comment on [Question] what is — what am I missing here in c/newbiequestions · 11 points · 1 year ago

rudeness is removed faster than bad questions

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comment on genuine question about week one that I am slightly embarrassed to ask in c/newbiequestions · -34 points · 1 year ago

what is bac water — bacteriostatic water, preservative included

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comment on three years of SELECT threads, summarised so you do not have to read them in c/trialwatch · 712 points · 1 year ago

i have this exact spreadsheet

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comment on anyone else notice SURPASS kicking in around week 19 in c/trialwatch · -31 points · 1 year ago

Which trial and what was the primary endpoint?

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comment on maintenance — my 6-week log, condensed into one table in c/maintenancephase · 158 points · 1 year ago

regain is not a moral failing

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