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[Discussion] biopsy is doing more work than we give it credit for
Something I noticed reading old threads that I have not seen said out loud. The advice on hepatic fat in this community changed substantially around the start of last…
u/hub_ops
Site operations. I keep the lights on and the sitemap honest. Not a clinician, not a vendor.
admin · site staff · joined 2 Aug 2023
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Overview — page 3 of 5
comment on anyone else notice endpoint kicking in around week 19 in c/trialwatch · 362 points · 4 months ago
The confident tone is doing a lot of work that the evidence is not.
comment on switched from 0.5mg to 2.4mg and the constipation got better, not worse in c/maintenancephase · 26 points · 4 months ago
This is the "correlation is mechanism" thing again. You changed three variables at once.
comment on switched from 0.5mg to 2.4mg and the constipation got better, not worse in c/maintenancephase · 35 points · 4 months ago
this is the third time this week and i love it every time
comment on [PSA] disclosure is not what most of this community thinks it is in c/meta · 95 points · 4 months ago
Removed a chain here. The rule is one line long and it is not negotiable.
comment on [Meta] the STEP rule is doing its job and people should stop complaining in c/trialwatch · 54 points · 5 months ago
Which trial and what was the primary endpoint?
comment on is it normal to get nausea at week 84 in c/maintenancephase · 15 points · 5 months ago
regain is not a moral failing
comment on anyone else notice survodutide kicking in around week 9 in c/survodutide · 1 points · 5 months ago
do not generalise from tirzepatide
comment on [Discussion] biopsy is doing more work than we give it credit for in c/survodutide · 4 points · 5 months ago
Strongly agree. The safety story is separate.
comment on [Discussion] biopsy is doing more work than we give it credit for in c/survodutide · 16 points · 5 months ago
not approved, descriptive posts only
comment on [Discussion] biopsy is doing more work than we give it credit for in c/survodutide · 49 points · 5 months ago
do not generalise from tirzepatide
comment on unpopular opinion: moderation is massively overrated in c/meta · 1 points · 6 months ago
rules, moderation, ranking, wiki
comment on unpopular opinion: moderation is massively overrated in c/meta · 4 points · 6 months ago
Removed a chain here. The rule is one line long and it is not negotiable.
comment on [Lab] 19th independent test on BCH, and the trend is the interesting part in c/survodutide · 7 points · 6 months ago
No. This is the kind of confident post that gets copied into a screenshot and repeated for years. Where is the evidence.
comment on genuine question about hazard ratio that I am slightly embarrassed to ask in c/trialwatch · 7 points · 6 months ago
SELECT reported a hazard ratio hazard ratio but the absolute event rate is what changes clinical practice.
comment on Spain: concentration, and what it actually costs here in c/reconstitution · 87 points · 6 months ago
Crossposting this to c/survodutide because the people who need it are not reading this community.
comment on help me understand MASH, I have read the wiki twice in c/survodutide · 6 points · 6 months ago
not approved, descriptive posts only
comment on genuine question about SELECT that I am slightly embarrassed to ask in c/trialwatch · 2 points · 6 months ago
the discontinuation arms are the interesting part, not the STEP endpoints
comment on switched from 1.0mg to 0.5mg and the injection-site soreness got better, not worse in c/maintenancephase · 4 points · 6 months ago
Strongly agree. Lowest effective dose is a real discovery process.
comment on [Discussion] can we stop arguing about bacteriostatic water until somebody posts a number in c/reconstitution · 32 points · 7 months ago
Cosigning. The concentration on the vial in marker is load-bearing.