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admin · site staff · joined 2 Aug 2023

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comment on mg ÷ mL, that is the whole formula, why did i find this hard in c/reconstitution · 3 points · 1 days ago

This is correct. 2mL versus 9mL is the common mistake.

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comment on [Meta] how the ranking actually works, with the formula in c/meta · 96 points · 1 days ago

reasonable. adding a line to the about page rather than the front page, but the point is taken.

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comment on [Meta] how the ranking actually works, with the formula in c/meta · 154 points · 2 days ago

correct, and it is why controversial is my own default browse. it is a disagreement detector rather than a quality detector, which are different tools.

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comment on [Meta] how the ranking actually works, with the formula in c/meta · 143 points · 2 days ago

anyone motivated enough to game it can infer it from the orderings in an afternoon. the only people a secret formula protects are the people running it.

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comment on [Meta] how the ranking actually works, with the formula in c/meta · 84 points · 2 days ago

it does not. the formulas are the whole system, which means they are also the whole vulnerability. we handle that socially rather than algorithmically and we are open about the trade.

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comment on [Readout] SELECT: MACE HR 0.80, and the absolute numbers people skip in c/trialwatch · 10 points · 2 days ago

Strongly agree. Phase 2 is investigational, not conclusive.

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comment on [Paper] SURMOUNT-4 withdrawal arm, read the appendix not the abstract in c/trialwatch · 15 points · 3 days ago

This is the "correlation is mechanism" thing again. You changed three variables at once.

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comment on [Explainer] why 1mL syringes cause overdoses and 0.3mL ones do not in c/reconstitution · 13 points · 3 days ago

That is net peptide content, not purity. Different number, different meaning.

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comment on is the tirz appetite thing actually different or am i imagining it in c/tirzepatide · 19 points · 4 days ago

Three years on this site and the questions have not changed at all. Which is depressing or reassuring depending on the day.

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comment on sterile water is not bacteriostatic water and it is not close in c/reconstitution · 20 points · 4 days ago

bacteriostatic and sterile water are not interchangeable, do not use them that way

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comment on [Math] someone check my arithmetic before i draw this up in c/reconstitution · 21 points · 9 days ago

Is that 5mg vial or 21mg?

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comment on GIP agonism explained like i am five, please in c/tirzepatide · 12 points · 9 days ago

That is net peptide content, not purity. Different number, different meaning.

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comment on [Question] does anyone actually feel "done" or is that not a thing in c/maintenancephase · -33 points · 13 days ago

The plateau is real and boring. 48 weeks at the same weight, then movement again. Patience was the intervention.

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comment on [Meta] how the ranking actually works, with the formula in c/meta · 12 points · 14 days ago

the moderation decision is logged

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comment on SURMOUNT-1 was -20.9% at 72 weeks. that is the number, not -30% in c/tirzepatide · 36 points · 16 days ago

nope, the equivalence to semaglutide is not known, comparing 15mg tirz to 2.4mg sema is guessing

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comment on [Trial Data] nausea rates in the combination arm vs sema alone in c/cagrilintide · 47 points · 16 days ago

REDEFINE which arm?

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comment on [Stats] number needed to treat, or i am not interested in c/trialwatch · 29 points · 19 days ago

the discontinuation arms are the interesting part, not the STEP endpoints

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comment on 24 months in and insulin syringe is still the thing I get wrong in c/reconstitution · 0 points · 22 days ago

show your working or it is unhelpful

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comment on stretching to 10 days instead of 7 — anyone doing this long term in c/maintenancephase · 38 points · 25 days ago

dose-stretching experiences welcome, dose-stretching instructions are not

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comment on [Long Term] what my labs look like three years in in c/maintenancephase · 23 points · 27 days ago

What dose are you on?

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