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u/honest_syringe_maybe

Not a chemist. Increasingly acting like one.

member · joined 11 Apr 2025

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comment on mg ÷ mL, that is the whole formula, why did i find this hard in c/reconstitution · 25 points · 2 days ago

stopper coring on the 6th draw because you keep using the same entry point. rotate.

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comment on [Question] small molecule means purity testing is a different problem, right in c/orforglipron · 75 points · 5 days ago

What was the batch number and which service?

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comment on cored the stopper on day 9. rotate your puncture site in c/reconstitution · 1 points · 6 days ago

I am going to push back on this slightly.

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comment on [Speculation] what happens to the research-peptide supply chain if this lands in c/orforglipron · 1 points · 6 days ago

Strongly agree. The supply impact would be huge.

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comment on [Country] SE/NO/DK — Norway is the outlier and not in a good way in c/glp1eu · 6 points · 9 days ago

The confident tone is doing a lot of work that the evidence is not.

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comment on [Math] someone check my arithmetic before i draw this up in c/reconstitution · 3 points · 9 days ago

more water means more units for the same dose, which means finer resolution

Adding to this: dead space is doing more work than the comment implies.

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comment on [Results] 21 weeks on 0.5mg, full numbers, ask me anything boring in c/glp1eu · 6 points · 24 days ago

This is the "correlation is mechanism" thing again. You changed three variables at once.

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comment on [Question] how do you actually verify mg/mL in c/reconstitution · 2 points · 1 months ago

Are you using a u-100 or u-40 syringe? That changes everything.

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comment on [Discussion] we are measuring small molecule at the wrong time and calling it noise in c/orforglipron · 1 points · 1 months ago

Yeah, small molecule changes the whole game.

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comment on [Results] 26 weeks on 5mg, full numbers, ask me anything boring in c/reconstitution · 53 points · 1 months ago

Water content matters more than people think. If a vial is carrying residual moisture, your "10mg" is not 10mg of peptide.

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comment on week 71 check-in — 6kg down, constipation manageable, one thing confusing me in c/reconstitution · 8 points · 1 months ago

Small correction: the trial was 15 weeks, not 23. Does not change your point but people will quote it.

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comment on prescription: the version I wish someone had shown me in week 1 in c/glp1eu · 6 points · 2 months ago

Disagree but this is the good kind of wrong — it is specific enough to be checked.

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comment on tried EU for 16 weeks. here is what happened. in c/glp1eu · 37 points · 2 months ago

apotheke, receta, pharmacy — twenty-seven different answers

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comment on ATTAIN — 3 things I got wrong before I got it right in c/orforglipron · -6 points · 3 months ago

phase 8 data is interesting, phase 32 will tell the real story

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comment on ATTAIN — 3 things I got wrong before I got it right in c/orforglipron · 41 points · 3 months ago

The thing nobody prepared me for was the quiet. Not the appetite, the quiet. The constant negotiation in my head about food just stopped.

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comment on ATTAIN — 3 things I got wrong before I got it right in c/orforglipron · 74 points · 3 months ago

Came off after 43 weeks for financial reasons. Regained about a third over the following year. Back on now at a much lower dose.

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comment on [Discussion] can we stop arguing about EU until somebody posts a number in c/glp1eu · 4 points · 4 months ago

pharmacy stock varies by country and season

Counter-anecdote: opposite result, same dose. Which mostly tells us the variance is huge.

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comment on [Discussion] can we stop arguing about EU until somebody posts a number in c/glp1eu · 24 points · 4 months ago

You have restated the marketing copy. What is the actual substance here.

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comment on France: EU, and what it actually costs here in c/glp1eu · 22 points · 4 months ago

the 4-country variation is the whole point

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comment on the ACHIEVE question that gets asked weekly, answered properly in c/orforglipron · 61 points · 6 months ago

phase 2 data is interesting, phase 25 will tell the real story

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