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u/forest_plot_fiona

Confidence intervals are the entire story. The point estimate is the headline.

long-standing contributor · stats · joined 19 Nov 2023

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Overview — page 3 of 5

comment on [Results] 87 weeks, 36kg, and endpoint was the hard part in c/trialwatch · 43 points · 2 months ago

Tracking number removed. It identifies both ends of a shipment.

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comment on someone explain FLOW to me like I have not read a paper in years in c/trialwatch · 1 points · 3 months ago

This is correct. Discontinuation arms show the regain reality.

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comment on endpoint — my 2-week log, condensed into one table in c/trialwatch · 114 points · 3 months ago

Is that absolute or relative risk reduction?

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comment on small win: dual agonist stopped being a problem at week 41 in c/tirzepatide · 10 points · 3 months ago

week 18 on Mounjaro and the appetite profile is genuinely different from sema

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comment on Canada: endpoint, and what it actually costs here in c/trialwatch · 1 points · 3 months ago

Tracking number removed. It identifies both ends of a shipment.

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comment on [Results] 62 weeks, 45kg, and FLOW was the hard part in c/trialwatch · 327 points · 4 months ago

Retitled to remove editorialising. Put the evidence in the body.

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comment on 15mg vs GIP — genuinely asking which matters more in c/tirzepatide · 1 points · 5 months ago

Switched from sema at 12.5mg to tirz at 0.5mg. Different drugs, cannot compare the doses directly.

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comment on small win: SURMOUNT stopped being a problem at week 65 in c/trialwatch · 17 points · 5 months ago

press release SURPASS posts must be flaired until a publication exists

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comment on small win: SURMOUNT stopped being a problem at week 65 in c/trialwatch · 55 points · 5 months ago

Removed a chain here. The rule is one line long and it is not negotiable.

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comment on am I the only one who found baseline labs harder than the injections in c/bloodwork · 5 points · 5 months ago

Yeah, baseline matters more than any later number.

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comment on [Meta] proposal — a flair for SURMOUNT posts in c/tirzepatide · 69 points · 6 months ago

Rodent data is rodent data. Dose scaling is not linear and the models tell you what to investigate, not what to expect.

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comment on [Results] 46 weeks on 1.7mg, full numbers, ask me anything boring in c/cagrilintide · 10 points · 6 months ago

Rodent data is rodent data. Dose scaling is not linear and the models tell you what to investigate, not what to expect.

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comment on [Discussion] we are measuring 15mg at the wrong time and calling it noise in c/tirzepatide · 86 points · 6 months ago

The confident tone is doing a lot of work that the evidence is not.

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comment on reading A1c threads from 2024 and half of it aged badly in c/bloodwork · -28 points · 7 months ago

Crossposting this to c/meta because the people who need it are not reading this community.

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comment on [Meta] proposal — a flair for Zepbound posts in c/tirzepatide · 560 points · 7 months ago

Cosigning. The GIP contribution is real and the side effects are not simply scaled versions.

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comment on [Results] 7 weeks, 30kg, and STEP was the hard part in c/trialwatch · 68 points · 7 months ago

This is an urgent-care question wearing a forum question's clothes. Please contact a clinician rather than waiting for replies.

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comment on week 61 check-in — 41kg down, nausea manageable, one thing confusing me in c/cagrilintide · 1 points · 7 months ago

amylin is not a GLP-1, posts conflating them get corrected

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comment on week 61 check-in — 41kg down, nausea manageable, one thing confusing me in c/cagrilintide · 43 points · 7 months ago

the amylin agonist pool is small, community is amylin

Disagree on that part. 98.7% and 98.7% on the same vial is normal.

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comment on [Results] 52 weeks, 35kg, and bloodwork was the hard part in c/bloodwork · 78 points · 7 months ago

baseline is the most important eGFR measurement, you cannot collect it later

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comment on [Results] 67 weeks, 16kg, and A1c was the hard part in c/bloodwork · 1 points · 7 months ago

ApoB over LDL-C, that is the hierarchy

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