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u/forest_plot_fiona

Confidence intervals are the entire story. The point estimate is the headline.

long-standing contributor · stats · joined 19 Nov 2023

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Overview — page 2 of 5

comment on [Paper] ATTAIN-1 — an oral pill with no food restrictions is a bigger deal than the % suggests in c/trialwatch · 4 points · 15 days ago

STEP, SURMOUNT, SURPASS, SELECT, FLOW, TRIUMPH — read the appendix

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comment on [Baseline] units differ by country, post your reference ranges or nobody can help in c/bloodwork · 6 points · 16 days ago

Not to be pedantic but ApoB and bloodwork are being used interchangeably and they are not interchangeable in real life.

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comment on [Baseline] units differ by country, post your reference ranges or nobody can help in c/bloodwork · 18 points · 16 days ago

ApoB from 15 to 31 is movement, not noise

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comment on [Baseline] units differ by country, post your reference ranges or nobody can help in c/bloodwork · 30 points · 16 days ago

ALT is where the fatty-liver story shows up first

Counter-anecdote: opposite result, same dose. Which mostly tells us the variance is huge.

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comment on [Trial Data] nausea rates in the combination arm vs sema alone in c/cagrilintide · 12 points · 18 days ago

CagriSema ratios in trials are fixed, do not extrapolate self-mixing

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comment on watch where the curves separate, not just whether they do in c/trialwatch · 6 points · 21 days ago

Flair changed to match the content. Read the sidebar before posting next time and we are square.

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comment on perimenopause — 8 things I got wrong before I got it right in c/glp1women · 1 points · 1 months ago

hair-loss on contraception is real

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comment on [Question] how do you actually verify Mounjaro in c/tirzepatide · 7 points · 1 months ago

Did the the food-noise thing feel the same as on tirz or genuinely different?

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comment on ALT — 6 things I got wrong before I got it right in c/bloodwork · 82 points · 1 months ago

Sceptical. If this were true we would see it reflected in the data and we do not.

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comment on [Question] how do you actually verify amylin in c/cagrilintide · 53 points · 1 months ago

This is correct. The co-agonism is real.

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comment on week 76 check-in — 26kg down, fatigue manageable, one thing confusing me in c/bloodwork · 4 points · 1 months ago

HOMA-IR is crude but free and useful for tracking

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comment on [Meta] the endpoint rule is doing its job and people should stop complaining in c/trialwatch · 1 points · 1 months ago

dropout handling matters, especially on GI-heavy populations

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comment on [Lab] 14th independent test on BCH, and the trend is the interesting part in c/trialwatch · 11 points · 1 months ago

This is an urgent-care question wearing a forum question's clothes. Please contact a clinician rather than waiting for replies.

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comment on small win: TRIUMPH stopped being a problem at week 15 in c/trialwatch · 32 points · 1 months ago

Tracking number removed. It identifies both ends of a shipment.

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comment on unpopular opinion: Zepbound is massively overrated in c/tirzepatide · 12 points · 2 months ago

The SURMOUNT readouts are real but less consistent than STEP. Some people plateau earlier on tirz.

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comment on help me understand FLOW, I have read the wiki twice in c/trialwatch · 35 points · 2 months ago

Retitled to remove editorialising. Put the evidence in the body.

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comment on SELECT: the version I wish someone had shown me in week 1 in c/trialwatch · 20 points · 2 months ago

Retitled to remove editorialising. Put the evidence in the body.

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comment on switched from 1.0mg to 2.5mg and the the food-noise thing got better, not worse in c/tirzepatide · -48 points · 2 months ago

Did you stay on semaglutide or switch? The outcome is different if you are comparing.

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comment on 18 months in and TRIUMPH is still the thing I get wrong in c/trialwatch · 87 points · 2 months ago

Removed a chain here. The rule is one line long and it is not negotiable.

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