u/forest_plot_fiona
Confidence intervals are the entire story. The point estimate is the headline.
long-standing contributor · stats · joined 19 Nov 2023
Comments — page 3 of 5
comment on endpoint — my 2-week log, condensed into one table in c/trialwatch · 114 points · 3 months ago
Is that absolute or relative risk reduction?
comment on small win: dual agonist stopped being a problem at week 41 in c/tirzepatide · 10 points · 3 months ago
week 18 on Mounjaro and the appetite profile is genuinely different from sema
comment on Canada: endpoint, and what it actually costs here in c/trialwatch · 1 points · 3 months ago
Tracking number removed. It identifies both ends of a shipment.
comment on [Results] 62 weeks, 45kg, and FLOW was the hard part in c/trialwatch · 327 points · 4 months ago
Retitled to remove editorialising. Put the evidence in the body.
comment on 15mg vs GIP — genuinely asking which matters more in c/tirzepatide · 1 points · 5 months ago
Switched from sema at 12.5mg to tirz at 0.5mg. Different drugs, cannot compare the doses directly.
comment on small win: SURMOUNT stopped being a problem at week 65 in c/trialwatch · 17 points · 5 months ago
press release SURPASS posts must be flaired until a publication exists
comment on small win: SURMOUNT stopped being a problem at week 65 in c/trialwatch · 55 points · 5 months ago
Removed a chain here. The rule is one line long and it is not negotiable.
comment on am I the only one who found baseline labs harder than the injections in c/bloodwork · 5 points · 5 months ago
Yeah, baseline matters more than any later number.
comment on [Meta] proposal — a flair for SURMOUNT posts in c/tirzepatide · 69 points · 6 months ago
Rodent data is rodent data. Dose scaling is not linear and the models tell you what to investigate, not what to expect.
comment on [Results] 46 weeks on 1.7mg, full numbers, ask me anything boring in c/cagrilintide · 10 points · 6 months ago
Rodent data is rodent data. Dose scaling is not linear and the models tell you what to investigate, not what to expect.
comment on [Discussion] we are measuring 15mg at the wrong time and calling it noise in c/tirzepatide · 86 points · 6 months ago
The confident tone is doing a lot of work that the evidence is not.
comment on reading A1c threads from 2024 and half of it aged badly in c/bloodwork · -28 points · 7 months ago
Crossposting this to c/meta because the people who need it are not reading this community.
comment on [Meta] proposal — a flair for Zepbound posts in c/tirzepatide · 560 points · 7 months ago
Cosigning. The GIP contribution is real and the side effects are not simply scaled versions.
comment on [Results] 7 weeks, 30kg, and STEP was the hard part in c/trialwatch · 68 points · 7 months ago
This is an urgent-care question wearing a forum question's clothes. Please contact a clinician rather than waiting for replies.
comment on week 61 check-in — 41kg down, nausea manageable, one thing confusing me in c/cagrilintide · 1 points · 7 months ago
amylin is not a GLP-1, posts conflating them get corrected
comment on week 61 check-in — 41kg down, nausea manageable, one thing confusing me in c/cagrilintide · 43 points · 7 months ago
the amylin agonist pool is small, community is amylin
Disagree on that part. 98.7% and 98.7% on the same vial is normal.
comment on [Results] 52 weeks, 35kg, and bloodwork was the hard part in c/bloodwork · 78 points · 7 months ago
baseline is the most important eGFR measurement, you cannot collect it later
comment on [Results] 67 weeks, 16kg, and A1c was the hard part in c/bloodwork · 1 points · 7 months ago
ApoB over LDL-C, that is the hierarchy
comment on SURPASS — 5 things I got wrong before I got it right in c/tirzepatide · 41 points · 7 months ago
What was the trial arm you are quoting from? SURMOUNT-1, -2, -3 are all different.
comment on [Question] SURPASS — what am I missing here in c/tirzepatide · 10 points · 8 months ago
Disagree. What you are describing is consistent with Zepbound, not with what you concluded.