u/first_hundred
Member #63. The c/coa rules were my idea and I regret nothing.
long-standing contributor · joined 19 Aug 2023
Comments — page 2 of 5
comment on what changed for me between week 30 and week 73 in c/coa · 19 points · 2 months ago
Slight fix: the number was 99.1, not 96.8. Decimal point, but a fairly consequential one.
comment on [Question] method development — what am I missing here in c/hplc · 6 points · 3 months ago
Did they post the raw trace or just the summary?
comment on endpoint — my 2-week log, condensed into one table in c/trialwatch · 18 points · 3 months ago
No. This is the kind of confident post that gets copied into a screenshot and repeated for years. Where is the evidence.
comment on [Meta] proposal — a flair for certificate of analysis posts in c/coa · 49 points · 3 months ago
No. This is the kind of confident post that gets copied into a screenshot and repeated for years. Where is the evidence.
comment on [Meta] proposal — a flair for certificate of analysis posts in c/coa · 28 points · 3 months ago
Tested the GLB raw material and a reseller vial side-by-side. Same purity claim, different impurity profiles. Handling matters.
comment on [Meta] proposal — a flair for certificate of analysis posts in c/coa · 86 points · 3 months ago
Dead space in the needle hub holds a small but non-trivial volume. On low-volume draws that can be several units.
comment on [Results] 42 weeks, 21kg, and purity was the hard part in c/coa · -3 points · 3 months ago
Titration speed is a side-effect dial far more than an efficacy dial.
comment on [Question] New Zealand — has anyone got a straight answer on certificate of analysis in c/coa · 8 points · 3 months ago
the counterion is part of the mass you paid for
comment on [Meta] the FLOW rule is doing its job and people should stop complaining in c/trialwatch · 2 points · 4 months ago
Slight fix: the number was 97.6, not 98.9. Decimal point, but a fairly consequential one.
comment on [Meta] the FLOW rule is doing its job and people should stop complaining in c/trialwatch · 4 points · 4 months ago
Phase 2 TRIUMPH looked amazing. Phase 3 trials are harder. Do not anchor on phase 2 readouts.
comment on [Meta] the FLOW rule is doing its job and people should stop complaining in c/trialwatch · 5 points · 4 months ago
the relative risk reduction in headlines is not the whole story
comment on COA: what the trials say vs what this community says in c/coa · -11 points · 4 months ago
no "is this good?" without saying what the compound and claimed purity are
comment on [Results] 62 weeks, 45kg, and FLOW was the hard part in c/trialwatch · 1 points · 4 months ago
press release STEP posts must be flaired until a publication exists
Adding to this: SURMOUNT is doing more work than the comment implies.
comment on water content — 5 things I got wrong before I got it right in c/coa · 104 points · 4 months ago
Tracking number removed. It identifies both ends of a shipment.
comment on anyone else notice endpoint kicking in around week 19 in c/trialwatch · 1 points · 4 months ago
the relative risk reduction in headlines is not the whole story
Adding to this: hazard ratio is doing more work than the comment implies.
comment on the LC-MS question that gets asked weekly, answered properly in c/hplc · 1 points · 5 months ago
Not to be pedantic but method development and integration are being used interchangeably and they are not interchangeable in real life.
comment on nobody warned me about nausea and I would have liked the warning in c/coa · 567 points · 5 months ago
Flair changed to match the content. Read the sidebar before posting next time and we are square.
comment on [Vendor] WXT order #6 — the Netherlands, 31 days, no drama, receipts inside in c/trialwatch · 85 points · 5 months ago
Three years on this site and the questions have not changed at all. Which is depressing or reassuring depending on the day.
comment on [Lab] SGN BPC — VendorInvestigate came back 93.7% against a claimed 94.2% in c/coa · 364 points · 6 months ago
the counterion is part of the mass you paid for
comment on the Netherlands: purity, and what it actually costs here in c/hplc · 83 points · 6 months ago
integration decision on a shoulder changes your number by half a point on its own