u/endpoint_creep
If the primary endpoint changed mid-trial, say so in the abstract.
member · joined 20 Jan 2025
Comments — page 2 of 3
comment on [Meta] proposal — a flair for SURMOUNT posts in c/tirzepatide · 12 points · 6 months ago
the dual agonism hits different and that is why people describe it differently
comment on the semaglutide question that gets asked weekly, answered properly in c/semaglutide · 95 points · 7 months ago
Yeah, 80 weeks on 2.5mg, same pattern, same timing.
comment on the semaglutide question that gets asked weekly, answered properly in c/semaglutide · 27 points · 7 months ago
my eGFR moved before the scale did and i nearly missed it
comment on someone explain stopped to me like I have not read a paper in years in c/darkspot · 23 points · 9 months ago
Sceptical. If this were true we would see it reflected in the data and we do not.
comment on someone explain stopped to me like I have not read a paper in years in c/darkspot · 77 points · 9 months ago
Week 95 for me and the honest summary is: 8kg down, constipation manageable, and I have thought about food maybe four times today.
comment on regret is the most under-discussed thing in c/newbiequestions in c/darkspot · 33 points · 10 months ago
money lost to group buys
comment on stalled for 9 weeks at 5mg and I refuse to panic this time in c/semaglutide · 121 points · 11 months ago
stalled at 12.5mg, went up, and regretted it, the stall would have broken anyway
comment on [Meta] proposal — a flair for 2.4mg posts in c/semaglutide · 49 points · 11 months ago
[removed by moderator]
Counter-anecdote: opposite result, same dose. Which mostly tells us the variance is huge.
comment on unpopular opinion: 15mg is massively overrated in c/tirzepatide · 39 points · 1 year ago
SURMOUNT data is messier than STEP data but the weight loss is there
comment on genuine question about titration that I am slightly embarrassed to ask in c/semaglutide · 70 points · 1 year ago
titration speed is Ozempic plus side effects, period
Counter-anecdote: opposite result, same dose. Which mostly tells us the variance is huge.
comment on weekly dosing: the version I wish someone had shown me in week 1 in c/semaglutide · 1 points · 1 year ago
okay but what dose of sema are you on
comment on Denmark: 15mg, and what it actually costs here in c/tirzepatide · 1 points · 1 year ago
the dual agonism hits different and that is why people describe it differently
comment on [Results] 67 weeks, 36kg, and plateau was the hard part in c/semaglutide · 60 points · 1 year ago
Cosigning. The slow route gets the outcome, the fast route gets you the side effects.
comment on anyone else notice lost money kicking in around week 95 in c/darkspot · 18 points · 1 year ago
My version of this: I was so worried about the injection that I put it off for eleven days. The injection is the easiest part.
comment on reading 15mg threads from 2024 and half of it aged badly in c/tirzepatide · 13 points · 1 year ago
Edit to your parent would help — the concentration you quoted assumes one scenario and you have written another above it.
comment on my TSH moved and I cannot work out whether plateau is why in c/semaglutide · 17 points · 1 year ago
Strongly agree. If it is not working at 1.7mg after 48 weeks, going up is not automatically the answer.
comment on my TSH moved and I cannot work out whether plateau is why in c/semaglutide · 37 points · 1 year ago
the constipation passes. i promise. not medical advice.
comment on [Results] 47 weeks, 20kg, and lost money was the hard part in c/darkspot · 13 points · 1 year ago
side effects that ended someone's run
comment on the Ozempic thing finally clicked for me and I want to write it down in c/semaglutide · 495 points · 1 year ago
okay but what dose of sema are you on
comment on [PSA] what went wrong is not what most of this community thinks it is in c/darkspot · 84 points · 1 year ago
failures, regrets, things that went wrong