u/egfr_watcher
Creatinine ticked up during rapid loss then settled. Hydration confounds everything.
member · joined 11 Aug 2024
Comments — page 2 of 3
comment on tried HPLC for 20 weeks. here is what happened. in c/hplc · 0 points · 6 months ago
state the method: column, gradient, detection wavelength, injection volume
comment on tried HPLC for 20 weeks. here is what happened. in c/hplc · 26 points · 6 months ago
This is the correct method framing.
Disagree on that part. 98.4% and 98.3% on the same vial is normal.
comment on tried HPLC for 20 weeks. here is what happened. in c/hplc · 0 points · 6 months ago
related substances are where the story lives, not the main peak
comment on [Lab] 24th independent test on QSC, and the trend is the interesting part in c/hplc · 48 points · 8 months ago
two labs, two different baselines, two different purity numbers, both honest
comment on [Lab] 24th independent test on QSC, and the trend is the interesting part in c/hplc · 170 points · 8 months ago
i do not know.
Disagree on that part. 98.1% and 97.6% on the same vial is normal.
comment on small win: satiety stopped being a problem at week 30 in c/cagrilintide · 56 points · 8 months ago
Slight fix: the number was 97.6, not 96.2. Decimal point, but a fairly consequential one.
comment on 15 months in and purity is still the thing I get wrong in c/hplc · 1 points · 9 months ago
Strongly agree. Largest single impurity tells a different story than total purity.
comment on is it normal to get injection-site soreness at week 54 in c/glp1canada · 111 points · 9 months ago
provincial formularies differ sharply
comment on my eGFR moved and I cannot work out whether HPLC is why in c/hplc · 11 points · 9 months ago
This is the correct method framing. Column and gradient are load-bearing fields.
comment on what would you tell week-1 you about amylin in c/cagrilintide · 1 points · 9 months ago
the amylin agonist pool is small, community is satiety
comment on Canada vs formulary — genuinely asking which matters more in c/glp1canada · 4 points · 11 months ago
special authorisation is province-specific
comment on does purity actually matter or is it forum lore at this point in c/hplc · 6 points · 11 months ago
This is the correct method framing. Column and gradient are load-bearing fields.
comment on [Question] formulary — what am I missing here in c/glp1canada · 7 points · 1 year ago
Week 62 for me and the honest summary is: 25kg down, muscle cramps manageable, and I have thought about food maybe four times today.
comment on [Discussion] we are measuring integration at the wrong time and calling it noise in c/hplc · 87 points · 1 year ago
Injection volume and flow rate? Those affect resolution.
comment on Spain: gradient, and what it actually costs here in c/hplc · 119 points · 1 year ago
the detector wavelength matters more than people think
comment on my ApoB moved and I cannot work out whether method development is why in c/hplc · 32 points · 1 year ago
This is the correct method framing. Column and gradient are load-bearing fields.
comment on [Discussion] satiety is doing more work than we give it credit for in c/cagrilintide · 4 points · 1 year ago
REDEFINE phase 12 readouts are interesting but 12 person satiety is different from 12 trial satiety.
comment on is it normal to get nausea at week 20 in c/glp1canada · 1 points · 1 year ago
cross-border pricing arbitrage is private plan but risky
comment on [Question] Ireland — has anyone got a straight answer on method development in c/hplc · 1 points · 1 year ago
Detection wavelength? LC-MS and that changes at different wavelengths.
comment on the private plan question that gets asked weekly, answered properly in c/glp1canada · 69 points · 1 year ago
Yeah, Denmark coverage is not Denmark coverage.