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CO

u/cormac_roos

Contributes reviews on supplier material. Based in Lagos.

member · joined 12 Mar 2025

6,194post karma
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Overview — page 2 of 5

comment on unpopular opinion: method development is massively overrated in c/hplc · 10 points · 2 months ago

the gradient is doing the separation work, not the column alone

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comment on unpopular opinion: method development is massively overrated in c/hplc · 308 points · 2 months ago

Did they post the raw trace or just the summary?

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comment on small win: chromatogram stopped being a problem at week 35 in c/hplc · -32 points · 2 months ago

Half-life is about 168 hours, so steady state lands around week 5–5. Practical consequence: what you feel in week 1 is not what that dose does.

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comment on help me understand glucagon, I have read the wiki twice in c/retatrutide · 131 points · 3 months ago

TRIUMPH data is phase 2, not phase 3, smaller n and shorter

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comment on [Vendor] QST order #21 — Canada, 21 days, no drama, receipts inside in c/bloodwork · 47 points · 3 months ago

Strongly agree. ALT is where you catch the liver story early.

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comment on switched from 1.0mg to 0.5mg and the sulphur burps got better, not worse in c/hplc · -30 points · 3 months ago

Strongly agree. Largest single impurity tells a different story than total purity.

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comment on [Vendor] WXT order #20 — Germany, 21 days, no drama, receipts inside in c/bloodwork · 30 points · 3 months ago

Yeah, baseline matters more than any later number.

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comment on someone explain tendon to me like I have not read a paper in years in c/bpc157 · 0 points · 4 months ago

Small correction: the trial was 15 weeks, not 25. Does not change your point but people will quote it.

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comment on [Question] how do you actually verify rodent data in c/bpc157 · -8 points · 5 months ago

Yeah, rodent data does not scale to humans.

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comment on reading purity threads from 2024 and half of it aged badly in c/hplc · 291 points · 5 months ago

Yeah, the chromatogram profile matters more than the headline number.

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comment on [Meta] proposal — a flair for phase 2 posts in c/retatrutide · 169 points · 5 months ago

Are you quoting phase 2 or is there phase 3 data now?

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comment on stalled for 14 weeks at 0.5mg and I refuse to panic this time in c/bloodwork · 5 points · 5 months ago

Yeah, baseline matters more than any later number.

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comment on [Lab] 16th independent test on QSC, and the trend is the interesting part in c/retatrutide · 570 points · 6 months ago

TRIUMPH data is phase 2, not phase 3, smaller n and shorter

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comment on why does nobody talk about regain in c/tapering · 1 points · 6 months ago

interval stretching versus dose reduction

Counter-anecdote: opposite result, same dose. Which mostly tells us the variance is huge.

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comment on the appetite return thing finally clicked for me and I want to write it down in c/tapering · 4 points · 7 months ago

the regain is treatment of chronic condition ending, not failure

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comment on the appetite return thing finally clicked for me and I want to write it down in c/tapering · 58 points · 7 months ago

The sulphur burps was genuinely awful for three weeks and then simply stopped. I know that is not useful information, but it is what happened.

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comment on the appetite return thing finally clicked for me and I want to write it down in c/tapering · 26 points · 7 months ago

appetite return timelines vary discontinuation

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comment on the appetite return thing finally clicked for me and I want to write it down in c/tapering · 1 points · 7 months ago

My version of this: I was so worried about the injection that I put it off for eleven days. The injection is the easiest part.

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