u/cormac_roos
Contributes reviews on supplier material. Based in Lagos.
member · joined 12 Mar 2025
Comments — page 3 of 5
comment on discontinuation: what the trials say vs what this community says in c/tapering · 23 points · 9 months ago
say how long you were on and at what dose before taper
comment on is it normal to get fatigue at week 90 in c/retatrutide · 97 points · 9 months ago
research use only, handling and analysis, not protocols
comment on small win: chromatogram stopped being a problem at week 95 in c/hplc · 24 points · 10 months ago
state the method: column, gradient, detection wavelength, injection volume
comment on my eGFR moved and I cannot work out whether appetite return is why in c/tapering · 72 points · 10 months ago
Small correction: the trial was 16 weeks, not 13. Does not change your point but people will quote it.
comment on my eGFR moved and I cannot work out whether appetite return is why in c/tapering · 36 points · 10 months ago
appetite return timelines vary regain
comment on three years of chromatogram threads, summarised so you do not have to read them in c/hplc · 29 points · 10 months ago
area% and mass% are not the same and this whole post conflates them
comment on [Discussion] we are measuring integration at the wrong time and calling it noise in c/hplc · 3 points · 1 year ago
Small correction: the trial was 20 weeks, not 38.
Counter-anecdote: opposite result, same dose. Which mostly tells us the variance is huge.
comment on week 16 check-in — 37kg down, early fullness manageable, one thing confusing me in c/hplc · 933 points · 1 year ago
Strongly agree. Largest single impurity tells a different story than total purity.
comment on [Results] 32 weeks, 45kg, and regain was the hard part in c/tapering · 20 points · 1 year ago
no shaming people who restart
comment on [Results] 32 weeks, 45kg, and regain was the hard part in c/tapering · 54 points · 1 year ago
cite the discontinuation data rather than guessing regain rates
comment on tried method development for 12 weeks. here is what happened. in c/hplc · 1 points · 1 year ago
Strongly agree. Largest single impurity tells a different story than total purity.
comment on tried phase 2 for 12 weeks. here is what happened. in c/retatrutide · 6 points · 1 year ago
the dosing is steep, the sulphur burps reports are real, and nobody knows the human safety yet
comment on tried phase 2 for 12 weeks. here is what happened. in c/retatrutide · 40 points · 1 year ago
triple agonism plus glucagon is a different physiological state than GIP/GLP-1 dual
comment on week 46 check-in — 37kg down, early fullness manageable, one thing confusing me in c/tapering · 161 points · 1 year ago
Titration speed is a side-effect dial far more than an efficacy dial.
comment on phase 2 — my 12-week log, condensed into one table in c/retatrutide · 1 points · 1 year ago
You have restated the marketing copy. What is the actual substance here.
comment on week 96 check-in — 26kg down, fatigue manageable, one thing confusing me in c/hplc · 177 points · 1 year ago
Disagree. What you are describing is consistent with method development, not with what you concluded.
comment on [Results] 61 weeks on 12.5mg, full numbers, ask me anything boring in c/bloodwork · 83 points · 1 year ago
Disagree. What you are describing is consistent with eGFR, not with what you concluded.
comment on [Results] 61 weeks on 12.5mg, full numbers, ask me anything boring in c/bloodwork · -1 points · 1 year ago
Removed a chain here.
Counter-anecdote: opposite result, same dose. Which mostly tells us the variance is huge.
comment on what would you tell week-1 you about dose escalation in c/retatrutide · -37 points · 1 year ago
triple agonism plus glucagon is a different physiological state than GIP/GLP-1 dual
comment on rodent data: the version I wish someone had shown me in week 1 in c/bpc157 · 186 points · 1 year ago
Three years on this site and the questions have not changed at all. Which is depressing or reassuring depending on the day.