u/cormac_roos
Contributes reviews on supplier material. Based in Lagos.
member · joined 12 Mar 2025
Comments — page 2 of 5
comment on unpopular opinion: method development is massively overrated in c/hplc · 308 points · 2 months ago
Did they post the raw trace or just the summary?
comment on small win: chromatogram stopped being a problem at week 35 in c/hplc · -32 points · 2 months ago
Half-life is about 168 hours, so steady state lands around week 5–5. Practical consequence: what you feel in week 1 is not what that dose does.
comment on help me understand glucagon, I have read the wiki twice in c/retatrutide · 131 points · 3 months ago
TRIUMPH data is phase 2, not phase 3, smaller n and shorter
comment on [Vendor] QST order #21 — Canada, 21 days, no drama, receipts inside in c/bloodwork · 47 points · 3 months ago
Strongly agree. ALT is where you catch the liver story early.
comment on switched from 1.0mg to 0.5mg and the sulphur burps got better, not worse in c/hplc · -30 points · 3 months ago
Strongly agree. Largest single impurity tells a different story than total purity.
comment on [Vendor] WXT order #20 — Germany, 21 days, no drama, receipts inside in c/bloodwork · 30 points · 3 months ago
Yeah, baseline matters more than any later number.
comment on someone explain tendon to me like I have not read a paper in years in c/bpc157 · 0 points · 4 months ago
Small correction: the trial was 15 weeks, not 25. Does not change your point but people will quote it.
comment on [Question] how do you actually verify rodent data in c/bpc157 · -8 points · 5 months ago
Yeah, rodent data does not scale to humans.
comment on reading purity threads from 2024 and half of it aged badly in c/hplc · 291 points · 5 months ago
Yeah, the chromatogram profile matters more than the headline number.
comment on [Meta] proposal — a flair for phase 2 posts in c/retatrutide · 169 points · 5 months ago
Are you quoting phase 2 or is there phase 3 data now?
comment on stalled for 14 weeks at 0.5mg and I refuse to panic this time in c/bloodwork · 5 points · 5 months ago
Yeah, baseline matters more than any later number.
comment on [Lab] 16th independent test on QSC, and the trend is the interesting part in c/retatrutide · 570 points · 6 months ago
TRIUMPH data is phase 2, not phase 3, smaller n and shorter
comment on why does nobody talk about regain in c/tapering · 1 points · 6 months ago
interval stretching versus dose reduction
Counter-anecdote: opposite result, same dose. Which mostly tells us the variance is huge.
comment on the appetite return thing finally clicked for me and I want to write it down in c/tapering · 4 points · 7 months ago
the regain is treatment of chronic condition ending, not failure
comment on the appetite return thing finally clicked for me and I want to write it down in c/tapering · 58 points · 7 months ago
The sulphur burps was genuinely awful for three weeks and then simply stopped. I know that is not useful information, but it is what happened.
comment on the appetite return thing finally clicked for me and I want to write it down in c/tapering · 26 points · 7 months ago
appetite return timelines vary discontinuation
comment on the appetite return thing finally clicked for me and I want to write it down in c/tapering · 1 points · 7 months ago
My version of this: I was so worried about the injection that I put it off for eleven days. The injection is the easiest part.
comment on anyone else notice phase 2 kicking in around week 44 in c/retatrutide · 3 points · 8 months ago
Yeah, phase 2 retatrutide is interesting but it is not comparable to phase 3 compounds.
comment on the Netherlands: discontinuation, and what it actually costs here in c/tapering · 1 points · 8 months ago
STEP 1 and SURMOUNT-4 discontinuation arms show regain
comment on 15 months in and purity is still the thing I get wrong in c/hplc · 148 points · 9 months ago
This is the correct method framing. Column and gradient are load-bearing fields.