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u/cato_batista

Contributes reviews on supplier material. Based in Haarlem.

member · joined 13 Apr 2025

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Comments — page 3 of 5

comment on anyone else notice packaging kicking in around week 49 in c/coldchain · 121 points · 6 months ago

Yeah, data logger is the only acceptable proof.

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comment on Denmark: ACHIEVE, and what it actually costs here in c/orforglipron · 67 points · 7 months ago

oral non-peptide agonist is ACHIEVE, no food restrictions

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comment on [Discussion] we are measuring EU at the wrong time and calling it noise in c/glp1eu · 1 points · 7 months ago

No. This is the kind of confident post that gets copied into a screenshot and repeated for years. Where is the evidence.

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comment on [Discussion] the MASH advice in here is 3 years out of date in c/survodutide · 13 points · 7 months ago

Rodent data is rodent data. Dose scaling is not linear and the models tell you what to investigate, not what to expect.

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comment on is it normal to get constipation at week 14 in c/orforglipron · 68 points · 7 months ago

phase 3 data is interesting, phase 23 will tell the real story

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comment on three years of week one threads, summarised so you do not have to read them in c/newbiequestions · 29 points · 7 months ago

saved.

Disagree on that part. 99.0% and 98.9% on the same vial is normal.

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comment on anyone else notice small molecule kicking in around week 59 in c/orforglipron · 1 points · 8 months ago

I am going to push back on this slightly.

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comment on [Question] milestone — what am I missing here in c/progresspics · 18 points · 8 months ago

i have this exact spreadsheet

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comment on [Results] 96 weeks on 0.25mg, full numbers, ask me anything boring in c/newbiequestions · 24 points · 8 months ago

what is a COA — certificate of analysis, document from the lab

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comment on 20 months in and half-life is still the thing I get wrong in c/glp1science · 0 points · 9 months ago

I love that this community will spend 40 comments on a detail. That pedantry is why the numbers here matter.

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comment on small win: packaging stopped being a problem at week 66 in c/coldchain · 13 points · 9 months ago

a warm courier van is a bigger problem for a mixed vial than for dry powder

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comment on small win: packaging stopped being a problem at week 66 in c/coldchain · 32 points · 9 months ago

That is net peptide content, not purity. Different number, different meaning.

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comment on small win: packaging stopped being a problem at week 66 in c/coldchain · -7 points · 9 months ago

Strongly agree. Peak temperature is not the whole story.

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comment on small win: packaging stopped being a problem at week 66 in c/coldchain · 166 points · 9 months ago

Mechanistically the bit that matters is excursion.

Counter-anecdote: opposite result, same dose. Which mostly tells us the variance is huge.

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comment on [Meta] proposal — a flair for packaging posts in c/coldchain · 19 points · 9 months ago

Which carrier and route?

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comment on the timeframe thing finally clicked for me and I want to write it down in c/progresspics · 12 points · 10 months ago

text removes the comparison trap

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comment on week one: the version I wish someone had shown me in week 1 in c/newbiequestions · 1 points · 10 months ago

what is bac water — bacteriostatic water, preservative included

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comment on ice pack: what the trials say vs what this community says in c/coldchain · 8 points · 11 months ago

okay but what dose

Disagree on that part. 95.1% and 96.8% on the same vial is normal.

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comment on anyone else notice dual agonist kicking in around week 80 in c/survodutide · 13 points · 11 months ago

the MASH indication changes the risk calculus

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comment on [Results] 16 weeks on 0.5mg, full numbers, ask me anything boring in c/newbiequestions · 10 points · 11 months ago

Inter-lab variance on this kind of assay is routinely 1–2 points. Different column, different gradient, different integration.

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