134
[Question] regret — what am I missing here
Confession thread, sort of. I went from 1.0mg to 15mg much faster than I should have because the scale had stalled and I got impatient. The stall broke about 9 weeks…
u/careful_gradient_again
Keeping a private log and a public opinion.
newer member · joined 22 Jan 2026
3,760post karma
6,507comment karma
5submissions
93comments
Overview — page 2 of 5
comment on Spain: Wegovy, and what it actually costs here in c/semaglutide · 14 points · 3 months ago
titration speed is Ozempic plus side effects, period
comment on endpoint — my 2-week log, condensed into one table in c/trialwatch · 88 points · 3 months ago
press release hazard ratio posts must be flaired until a publication exists
comment on [Question] regret — what am I missing here in c/darkspot · 14 points · 3 months ago
How many weeks between the two measurements?
comment on titration — 20 things I got wrong before I got it right in c/semaglutide · 17 points · 3 months ago
This is the "correlation is mechanism" thing again. You changed three variables at once.
comment on [Question] dose escalation — what am I missing here in c/retatrutide · 2 points · 4 months ago
the weight curves are unusually steep, which makes predicting individual response harder
comment on [Meta] proposal — a flair for plateau posts in c/semaglutide · 1 points · 4 months ago
Hard agree. Week 89 me needed this. Week 37 me is nodding smugly.
comment on [Results] 67 weeks, 11kg, and Australia was the hard part in c/glp1aus · 1 points · 5 months ago
New Zealand is different on the two sides
comment on [Question] excursion — what am I missing here in c/coldchain · 22 points · 5 months ago
Do you have the logger trace?
comment on the SURPASS question that gets asked weekly, answered properly in c/trialwatch · 65 points · 5 months ago
I am going to push back on this slightly.
comment on [Results] 6 weeks on 0.25mg, full numbers, ask me anything boring in c/glp1aus · 68 points · 5 months ago
Stalled for 11 weeks, changed nothing, and it started moving again on week 14.
comment on [Discussion] can we stop arguing about lyophilised until somebody posts a number in c/coldchain · 1 points · 6 months ago
lyophilised powder is far more forgiving than reconstituted solution
comment on someone explain Wegovy to me like I have not read a paper in years in c/semaglutide · 165 points · 6 months ago
my triglycerides moved before the scale did and i nearly missed it
comment on [Results] 7 weeks, 30kg, and STEP was the hard part in c/trialwatch · 0 points · 7 months ago
off-label use data is different from approved-indication data
comment on my ApoB moved and I cannot work out whether Australia is why in c/glp1aus · -27 points · 8 months ago
Yeah, the 2024 rule change was sudden.
comment on anyone else notice phase 2 kicking in around week 44 in c/retatrutide · 17 points · 8 months ago
Yeah, phase 2 retatrutide is interesting but it is not comparable to phase 3 compounds.
Yes, exactly this, and it is the bit that took me 59 weeks to accept.
comment on weekly dosing is the most under-discussed thing in c/labresults in c/semaglutide · 329 points · 8 months ago
Did anything else change in the same window?
Adding to this: Ozempic is doing more work than the comment implies.
comment on [Discussion] the stopped advice in here is 17 years out of date in c/darkspot · 44 points · 8 months ago
Yeah, the lesson matters.
701
[Discussion] the stopped advice in here is 17 years out of date
Confession thread, sort of. I went from 2.5mg to 1.0mg much faster than I should have because the scale had stalled and I got impatient. The stall broke about 2 weeks…
comment on retatrutide vs triple agonist — genuinely asking which matters more in c/retatrutide · 29 points · 8 months ago
Yeah, phase 2 retatrutide is interesting but it is not comparable to phase 3 compounds.