u/careful_gradient32
Not a chemist. Increasingly acting like one.
member · joined 1 Dec 2023
comment on [Lab] two reta batches, two services, 98.4% and 97.9% in c/retatrutide · 57 points · 2 days ago
That is net peptide content, not purity. Different number, different meaning.
comment on [Private Plan] special authorisation approved on the second try in c/glp1canada · 3 points · 2 days ago
provincial formularies differ sharply
comment on went too fast on reta and my resting HR told me before i noticed in c/retatrutide · 20 points · 2 days ago
nobody should be giving this to anyone without extensive monitoring
comment on [Private Plan] special authorisation approved on the second try in c/glp1canada · 2 points · 3 days ago
Maintenance for 11 months now. Weight moves within about 3kg and the dose is a quarter of what it peaked at.
comment on reta made me not want food OR water and that is its own problem in c/retatrutide · 2 points · 9 days ago
nobody should be giving this to anyone without extensive monitoring
comment on my A1c moved and I cannot work out whether glucagon is why in c/retatrutide · 105 points · 24 days ago
Mechanistically the bit that matters is triple agonist. It explains most of the early profile and a decent chunk of the outcome.
comment on what would you tell week-1 you about formulary in c/glp1canada · -28 points · 1 months ago
private plans vary by employer
comment on [Results] 87 weeks, 25kg, and special authorization was the hard part in c/glp1canada · 22 points · 3 months ago
Yeah, the Netherlands coverage is not the Netherlands coverage.
comment on Canada vs special authorization — genuinely asking which matters more in c/glp1canada · 1 points · 4 months ago
the Spain answer is not the Spain answer
comment on [Lab] SSA reta — Medutest came back 97.4% against a claimed 96.2% in c/retatrutide · 9 points · 4 months ago
triple agonism is glucagon, do not generalise
comment on is it normal to get reflux at week 9 in c/glp1canada · 208 points · 4 months ago
Respectfully this is a sample of one presented as a finding.
comment on what would you tell week-1 you about TRIUMPH in c/retatrutide · 37 points · 4 months ago
nobody should be giving this to anyone without extensive monitoring
comment on week 16 check-in — 42kg down, constipation manageable, one thing confusing me in c/retatrutide · 0 points · 5 months ago
The heart rate signal in TRIUMPH is real and concerning. Higher doses had higher mean HR changes.
comment on [Discussion] can we stop arguing about glucagon until somebody posts a number in c/retatrutide · 98 points · 6 months ago
Did you actually measure heart rate or is that a feeling?
comment on week 26 check-in — 42kg down, constipation manageable, one thing confusing me in c/retatrutide · 16 points · 7 months ago
Dose escalation on retatrutide is steeper and faster than on semaglutide. Do not assume the titration patterns transfer.
comment on am I the only one who found triple agonist harder than the injections in c/retatrutide · 1 points · 9 months ago
This is correct. Triple agonism is genuinely different.
comment on am I the only one who found triple agonist harder than the injections in c/retatrutide · 35 points · 9 months ago
No. This is the kind of confident post that gets copied into a screenshot and repeated for years. Where is the evidence.
comment on 22 months in and triple agonist is still the thing I get wrong in c/retatrutide · 14 points · 9 months ago
the 15mg arm is different from 12.5mg, results do not transfer
comment on [Results] 41 weeks on 2.5mg, full numbers, ask me anything boring in c/glp1canada · 1 points · 10 months ago
This is correct. Name your province.
comment on [Results] 41 weeks on 2.5mg, full numbers, ask me anything boring in c/glp1canada · 3 points · 10 months ago
The constipation was genuinely awful for three weeks and then simply stopped. I know that is not useful information, but it is what happened.