Been lurking in c/trialwatch for about 8 months and finally have something worth posting. Short version: week 35, 0.5mg, and incretin is the bit I still cannot get a…
u/bastian_eriksen
Contributes reviews on supplier material. Based in Verona.
member · joined 16 Jul 2025
Overview — page 3 of 5
comment on stalled for 16 weeks at 0.5mg and I refuse to panic this time in c/glp1science · 1 points · 7 months ago
the 11-day half-life means week 11 is still ramp-up pharmacokinetically
Counter-anecdote: opposite result, same dose. Which mostly tells us the variance is huge.
comment on 12 months in and heart rate is still the thing I get wrong in c/sideeffects · -15 points · 7 months ago
ask your actual doctor, not us
comment on [Results] 11 weeks on 2.5mg, full numbers, ask me anything boring in c/glp1science · 181 points · 8 months ago
the half-life is incretin, affects steady state timing
comment on anyone else notice 15mg kicking in around week 24 in c/tirzepatide · 7 points · 8 months ago
Did you stay on semaglutide or switch? The outcome is different if you are comparing.
comment on [Question] Australia — has anyone got a straight answer on half-life in c/glp1science · 1 points · 8 months ago
Edit to your parent would help — the concentration you quoted assumes one scenario and you have written another above it.
comment on 20 months in and half-life is still the thing I get wrong in c/glp1science · 1 points · 9 months ago
glucagon-receptor contribution is pharmacology for dual and triple agonism
comment on 21 months in and sulphur burps is still the thing I get wrong in c/sideeffects · 74 points · 9 months ago
week 51 and the constipation is finally getting better
comment on tried gastric emptying for 14 weeks. here is what happened. in c/glp1science · 73 points · 10 months ago
receptor distribution matters, GLP-1 is not everywhere
comment on switched from 12.5mg to 10mg and the nausea got better, not worse in c/tirzepatide · 364 points · 10 months ago
Cosigning. The GIP contribution is real and the side effects are not simply scaled versions.
comment on anyone else notice SURMOUNT kicking in around week 20 in c/tirzepatide · 9 points · 11 months ago
Respectfully this is a sample of one presented as a finding.
comment on genuine question about appetite that I am slightly embarrassed to ask in c/glp1science · -16 points · 11 months ago
do not extrapolate rodent data to human dosing without saying so
comment on [Vendor] WXT order #17 — Germany, 9 days, no drama, receipts inside in c/glp1science · 20 points · 1 year ago
receptor distribution matters, GLP-1 is not everywhere
comment on [Vendor] WXT order #17 — Germany, 9 days, no drama, receipts inside in c/glp1science · 113 points · 1 year ago
Which paper are you quoting?
Yes, exactly this, and it is the bit that took me 43 weeks to accept.
comment on [Results] 42 weeks, 30kg, and hair loss was the hard part in c/sideeffects · 64 points · 1 year ago
Yeah, the muscle cramps hit on day 21 for me too, not day 1.
comment on reading Zepbound threads from 2024 and half of it aged badly in c/tirzepatide · 18 points · 1 year ago
Yeah, dual agonism does produce a different appetite profile than GLP-1 alone.
comment on metformin — 5 things I got wrong before I got it right in c/t2dglp1 · 366 points · 1 year ago
insulin and sulfonylurea interactions are real hypo risk
comment on [Question] how do you actually verify sulphur burps in c/sideeffects · 127 points · 1 year ago
constipation is real, boring, and fixable
comment on [Question] perimenopause — what am I missing here in c/glp1women · -2 points · 1 year ago
the trials mostly studied men, perimenopause skipped
comment on [Vendor] QST order #20 — Denmark, 39 days, no drama, receipts inside in c/tirzepatide · 36 points · 1 year ago
the GIP side does different things than the GLP-1 side, that is the point