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u/aurel_mwangi

Contributes reviews on supplier material. Based in Oulu.

member · joined 13 Apr 2025

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Overview — page 3 of 5

comment on switched from 0.5mg to 2.4mg and the constipation got better, not worse in c/maintenancephase · 27 points · 4 months ago

regain after taper is expected, plan for it

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comment on [Question] New Zealand — has anyone got a straight answer on constipation in c/sideeffects · 35 points · 5 months ago

nausea on day 2 is normal, nausea after week 15 is worth checking

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comment on the SURPASS question that gets asked weekly, answered properly in c/trialwatch · 37 points · 5 months ago

Disagree. What you are describing is consistent with SURPASS, not with what you concluded.

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comment on switched from 12.5mg to 10mg and the constipation got better, not worse in c/labresults · 104 points · 5 months ago

This result fits the template perfectly. Logged.

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comment on [Discussion] can we stop arguing about hair loss until somebody posts a number in c/sideeffects · 310 points · 6 months ago

early fullness at 2.4mg is different from 0.25mg

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comment on what changed for me between week 50 and week 4 in c/sideeffects · 65 points · 6 months ago

IANAD and neither is anyone upvoting this

Counter-anecdote: opposite result, same dose. Which mostly tells us the variance is huge.

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comment on my hs-CRP moved and I cannot work out whether FLOW is why in c/trialwatch · 10 points · 7 months ago

event rates are more informative than hazard ratios alone

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comment on my hs-CRP moved and I cannot work out whether FLOW is why in c/trialwatch · 56 points · 7 months ago

the discontinuation arms are the interesting part, not the SURMOUNT endpoints

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comment on three years of Medutest threads, summarised so you do not have to read them in c/labresults · 24 points · 7 months ago

the 97.4% result confirmed the vendor claim, that is the signal

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comment on tried hair loss for 14 weeks. here is what happened. in c/sideeffects · 1 points · 8 months ago

How many weeks in are you? 10 weeks is noise, 18 weeks is a trend.

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comment on [Discussion] the seizure advice in here is 22 years out of date in c/customs · 135 points · 8 months ago

This is correct. State your country always.

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comment on reading SURPASS threads from 2024 and half of it aged badly in c/trialwatch · 31 points · 8 months ago

event rates are more informative than hazard ratios alone

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comment on PeptideMeter vs batch — genuinely asking which matters more in c/labresults · 51 points · 8 months ago

Slight fix: the number was 97.6, not 98.1.

Yes, exactly this, and it is the bit that took me 88 weeks to accept.

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comment on [Results] 81 weeks on 12.5mg, full numbers, ask me anything boring in c/trialwatch · -31 points · 8 months ago

event rates are more informative than hazard ratios alone

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comment on [Results] 81 weeks on 12.5mg, full numbers, ask me anything boring in c/trialwatch · 201 points · 8 months ago

SURMOUNT-4 discontinuation arm showed regain. That is the reality of a chronic disease treatment, not a failure.

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comment on [Results] 81 weeks on 12.5mg, full numbers, ask me anything boring in c/trialwatch · 250 points · 8 months ago

Phase 2 TRIUMPH looked amazing. Phase 3 trials are harder. Do not anchor on phase 2 readouts.

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comment on help me understand seizure, I have read the wiki twice in c/customs · 93 points · 9 months ago

no advice on evading inspection or misdeclaring

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comment on three years of sulphur burps threads, summarised so you do not have to read them in c/sideeffects · 8 points · 10 months ago

How many weeks in are you? 4 weeks is noise, 5 weeks is a trend.

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