u/aurel_mwangi
Contributes reviews on supplier material. Based in Oulu.
member · joined 13 Apr 2025
Comments — page 2 of 5
comment on switched from 0.25mg to 1.7mg and the constipation got better, not worse in c/maintenancephase · 60 points · 2 months ago
saved.
Yes, exactly this, and it is the bit that took me 55 weeks to accept.
comment on [Discussion] Janoshik is doing more work than we give it credit for in c/labresults · 86 points · 2 months ago
template required: vendor / product / batch / service / method / result
comment on switched from 0.25mg to 1.7mg and the constipation got better, not worse in c/maintenancephase · 1 points · 2 months ago
regain is not a moral failing
comment on does basics actually matter or is it forum lore at this point in c/newbiequestions · 1 points · 2 months ago
I am going to push back on this slightly.
comment on does basics actually matter or is it forum lore at this point in c/newbiequestions · 1 points · 2 months ago
This is a good question, genuinely.
comment on what would you tell week-1 you about heart rate in c/sideeffects · 130 points · 2 months ago
Yeah, the nausea hit on day 11 for me too, not day 1.
comment on sulphur burps is the most under-discussed thing in c/orforglipron in c/sideeffects · 88 points · 2 months ago
Disagree. What you are describing is consistent with nausea, not with what you concluded.
comment on someone explain beginner to me like I have not read a paper in years in c/newbiequestions · 3 points · 3 months ago
Edit to your parent would help — the concentration you quoted assumes one scenario and you have written another above it.
comment on am I the only one who found normal harder than the injections in c/newbiequestions · 19 points · 3 months ago
is this normal week 3 — yes, probably
comment on [Results] 22 weeks, 45kg, and maintenance was the hard part in c/maintenancephase · 213 points · 3 months ago
Regain on a taper is expected. 13% back over 24 weeks, which matches the discontinuation data. Planned for it.
comment on three years of dose stretching threads, summarised so you do not have to read them in c/maintenancephase · 0 points · 3 months ago
Regain on a taper is expected. 6% back over 24 weeks, which matches the discontinuation data. Planned for it.
comment on switched from 5mg to 2.5mg and the nausea got better, not worse in c/maintenancephase · 0 points · 4 months ago
Yeah, maintenance is the boring part and the important part.
comment on [Question] the UK — has anyone got a straight answer on what is in c/newbiequestions · 63 points · 4 months ago
I love that this community will spend 40 comments on a detail. That pedantry is why the numbers here matter.
comment on [Results] 62 weeks, 45kg, and FLOW was the hard part in c/trialwatch · 83 points · 4 months ago
STEP 1 readout: 99.3% mean weight loss, absolute numbers matter. Spread around that mean is enormous.
comment on [Results] 62 weeks, 45kg, and FLOW was the hard part in c/trialwatch · 17 points · 4 months ago
Yeah, absolute numbers matter more than the press release.
comment on [Results] 62 weeks, 45kg, and FLOW was the hard part in c/trialwatch · 93 points · 4 months ago
SURMOUNT-4 discontinuation arm showed regain. That is the reality of a chronic disease treatment, not a failure.
comment on switched from 0.5mg to 2.4mg and the constipation got better, not worse in c/maintenancephase · 27 points · 4 months ago
regain after taper is expected, plan for it
comment on [Question] New Zealand — has anyone got a straight answer on constipation in c/sideeffects · 35 points · 5 months ago
nausea on day 2 is normal, nausea after week 15 is worth checking
comment on the SURPASS question that gets asked weekly, answered properly in c/trialwatch · 37 points · 5 months ago
Disagree. What you are describing is consistent with SURPASS, not with what you concluded.
comment on switched from 12.5mg to 10mg and the constipation got better, not worse in c/labresults · 104 points · 5 months ago
This result fits the template perfectly. Logged.