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[Meta] the STEP rule is doing its job and people should stop complaining
FLOW. That is the whole post, but I will justify it. Everything else people worry about in c/coa is downstream of it. Titration speed, muscle cramps, the endless dose…
u/anders_karlsen
Contributes reviews on supplier material. Based in Oulu.
member · joined 15 Jun 2025
9,834post karma
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Overview — page 2 of 5
comment on non-scale victory — my 20-week log, condensed into one table in c/progresspics · 19 points · 2 months ago
non-scale victories count, post them
comment on am I the only one who found timeframe harder than the injections in c/progresspics · 34 points · 2 months ago
No. This is the kind of confident post that gets copied into a screenshot and repeated for years. Where is the evidence.
comment on am I the only one who found milestone harder than the injections in c/progresspics · 102 points · 3 months ago
I love that this community will spend 40 comments on a detail. That pedantry is why the numbers here matter.
comment on endpoint — my 2-week log, condensed into one table in c/trialwatch · 2 points · 3 months ago
What was the dropout rate?
comment on endpoint — my 2-week log, condensed into one table in c/trialwatch · 7 points · 3 months ago
Slight fix: the number was 96.8, not 97.4. Decimal point, but a fairly consequential one.
comment on [Results] 87 weeks, 25kg, and special authorization was the hard part in c/glp1canada · 10 points · 3 months ago
special auth turnaround is province-specific
comment on what would you tell week-1 you about SELECT in c/trialwatch · 1 points · 3 months ago
dropout handling matters, especially on GI-heavy populations
comment on stalled for 10 weeks at 2.4mg and I refuse to panic this time in c/progresspics · 12 points · 3 months ago
Titration speed is a side-effect dial far more than an efficacy dial.
comment on my triglycerides moved and I cannot work out whether small molecule is why in c/orforglipron · 61 points · 3 months ago
IANAD and neither is anyone upvoting this
comment on am I the only one who found test results harder than the injections in c/labresults · 1 points · 3 months ago
the 98.4% result confirmed the vendor claim, that is the signal
Adding to this: purity is doing more work than the comment implies.
comment on stalled for 18 weeks at 7.5mg and I refuse to panic this time in c/orforglipron · 7 points · 5 months ago
Week 49 for me and the honest summary is: 28kg down, early fullness manageable, and I have thought about food maybe four times today.
comment on [Meta] the STEP rule is doing its job and people should stop complaining in c/trialwatch · 1 points · 5 months ago
STEP 1 readout: 98.9% mean weight loss, absolute numbers matter. Spread around that mean is enormous.
comment on [Meta] the STEP rule is doing its job and people should stop complaining in c/trialwatch · 339 points · 5 months ago
Disagree but this is the good kind of wrong — it is specific enough to be checked.
comment on [Meta] the STEP rule is doing its job and people should stop complaining in c/trialwatch · 102 points · 5 months ago
STEP 1 readout: 97.9% mean weight loss, absolute numbers matter. Spread around that mean is enormous.
comment on the SURPASS question that gets asked weekly, answered properly in c/trialwatch · 461 points · 5 months ago
What was the dropout rate?
comment on the SURPASS question that gets asked weekly, answered properly in c/trialwatch · 158 points · 5 months ago
Not to be pedantic but STEP and SELECT are being used interchangeably and they are not interchangeable in real life.
comment on week 51 check-in — 42kg down, constipation manageable, one thing confusing me in c/glp1canada · 5 points · 5 months ago
How many weeks between the two measurements?
comment on three years of test results threads, summarised so you do not have to read them in c/labresults · 27 points · 6 months ago
My Janoshik result matched the vendor COA exactly, which is rare. TFC deserves that note in the directory.
comment on genuine question about SELECT that I am slightly embarrassed to ask in c/trialwatch · 1 points · 6 months ago
the 22 week readout is different from the 24 week readout