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u/adnan_nascimento

Contributes reviews on supplier material. Based in Verona.

member · joined 17 Aug 2025

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comment on [Titration] 12 weeks per step is not too slow, it is just unfashionable in c/tirzepatide · 32 points · 14 days ago

This matches the trial data. SURMOUNT-1 was 93.7% body weight at 18 weeks.

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comment on SURMOUNT-1 was -20.9% at 72 weeks. that is the number, not -30% in c/tirzepatide · 208 points · 17 days ago

Week 21 on Mounjaro and 40kg down. The appetite reduction feels different from sema in ways I do not have words for yet.

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comment on anyone else find 15mg genuinely unpleasant with no extra loss in c/tirzepatide · 1 points · 17 days ago

the fatigue from tirz is different, not necessarily worse

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comment on small win: GIP stopped being a problem at week 31 in c/tirzepatide · 25 points · 1 months ago

Hard agree. The food noise disappears differently on the two compounds.

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comment on small win: GIP stopped being a problem at week 31 in c/tirzepatide · 16 points · 1 months ago

The SURMOUNT readouts are real but less consistent than STEP. Some people plateau earlier on tirz.

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comment on switched from 1.0mg to 2.5mg and the the food-noise thing got better, not worse in c/tirzepatide · 1 points · 2 months ago

dual agonism is SURPASS, do not generalise from semaglutide

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comment on [Discussion] the 15mg advice in here is 3 years out of date in c/tirzepatide · 49 points · 3 months ago

the GIP side does different things than the GLP-1 side, that is the point

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comment on tried tirzepatide for 23 weeks. here is what happened. in c/tirzepatide · 13 points · 3 months ago

Zepbound and Mounjaro are literally the same drug, the name is the only difference

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comment on someone explain 15mg to me like I have not read a paper in years in c/tirzepatide · 124 points · 4 months ago

the muscle cramps from tirz is different, not necessarily worse

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comment on [Vendor] QST order #10 — Spain, 27 days, no drama, receipts inside in c/tirzepatide · 35 points · 6 months ago

stalled on sema, tried tirz, and the curves were actually different shapes

Yes, exactly this, and it is the bit that took me 96 weeks to accept.

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comment on anyone else notice 15mg kicking in around week 24 in c/tirzepatide · 13 points · 8 months ago

SURMOUNT data is messier than STEP data but the weight loss is there

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comment on does Zepbound actually matter or is it forum lore at this point in c/tirzepatide · -8 points · 9 months ago

The confident tone is doing a lot of work that the evidence is not.

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comment on does Zepbound actually matter or is it forum lore at this point in c/tirzepatide · 83 points · 9 months ago

the reflux from tirz is different, not necessarily worse

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comment on what changed for me between week 25 and week 74 in c/tirzepatide · 139 points · 9 months ago

Strongly agree. Tirz is better than sema is not a claim without a comparator dose.

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comment on anyone else notice SURMOUNT kicking in around week 30 in c/tirzepatide · 1 points · 1 year ago

You have restated the marketing copy. What is the actual substance here.

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comment on anyone else notice SURMOUNT kicking in around week 80 in c/tirzepatide · 62 points · 1 year ago

The confident tone is doing a lot of work that the evidence is not.

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comment on dual agonist: what the trials say vs what this community says in c/tirzepatide · -10 points · 1 year ago

Three years on this site and the questions have not changed at all. Which is depressing or reassuring depending on the day.

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comment on [Question] GIP — what am I missing here in c/tirzepatide · 141 points · 1 year ago

the appetite change on tirz is more than just reduced hunger, it is different machinery

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comment on [PSA] Mounjaro is not what most of this community thinks it is in c/tirzepatide · 1 points · 2 years ago

the early fullness from tirz is different, not necessarily worse

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