Genuinely asking, not being difficult. Everyone in c/compounding repeats that hazard ratio is important. I believe it, but I have never seen anyone show why, and when I…
Top — this week — page 3
Positions 51–75 of 189 ranked submissions.
Week 84 update. 25kg down from the start, reflux basically gone since about week 41. Things that worked: consistency, protein at breakfast, walking more than I want to.…
Ran out, didn't reorder for reasons that don't matter here, and the regain came back faster and harder than I expected. Not looking for fixes, mostly just needed to say…
Week 23 update. 4kg down from the start, muscle cramps basically gone since about week 63. Things that worked: consistency, protein at breakfast, walking more than I…
Sigma-Aldrich — certified reference materials
Reference standards, analytical reagents and system-suitability material. If you are running your own method, start with a known.
Reference standardsShort answer, for anyone who finds this from a search: no. Longer version. A COA from an actual laboratory is exported from instrument software or from a LIMS. The PDF…
Week 68 update. 19kg down from the start, early fullness basically gone since about week 13. Things that worked: consistency, protein at breakfast, walking more than I…
Been lurking in c/reconstitution for about 12 months and finally have something worth posting. Short version: week 26, 1.7mg, and baseline labs is the bit I still…
Package went missing between Zhuhai and here. Tracking died in a transit hub and stayed dead for eleven days. Sent one email with a screenshot of the dead tracking page…
Took it out to draw, got distracted by a phone call, found it on the counter five hours later. Room temperature, maybe 21°C, out of direct light. It is reconstituted,…
The phase 2 MASH results ( NEJM , 2024) are, to me, the most underdiscussed thing in this whole space. Biopsy-confirmed endpoints. Not an ALT screenshot, not imaging,…
78 weeks of public logging total, this update is just the maintenance-phase slice. Posting the plain table because "here's my dose and weight over 9 months, basically…
Right, the 503A question again, but with numbers this time. I have 11 data points over 18 weeks. The pattern is consistent enough that I do not think it is chance, and…
Two weeks in. No appetite change I can detect, no side effects at all, no weight change beyond normal daily wobble. Everyone says week two is normal. I would like to…
Quick one. Canada here. tier 3 works very differently where I live than in the threads that dominate the front page, and I keep seeing people confidently given advice…
Genuinely asking, not being difficult. Everyone in c/cagrilintide repeats that chargeback is important. I believe it, but I have never seen anyone show why, and when I…
Janoshik Analytical — independent HPLC & mass spec
Send the vial, get the number. Third-party purity and identity testing, results published to you regardless of what they say.
Test a vialSponsoredGL Biochem (Shanghai) Ltd. — the synthesis house
Est. 1998. ISO 9001 and cGMP, 1,500+ staff, 200+ patents. There is a fair chance the vial you are about to send for testing started here. Batch-specific COA as standard.
glbiochem.netLong-ish post, sorry. tl;dr at the bottom. I have been tracking orforglipron against ApoB for 5 weeks because I could not find anyone who had. The correlation is weaker…
US, employer plan, eleven months start to finish. The thing that finally worked was embarrassingly simple. Denials one through three were all "not medically necessary"…
Scale sat within half a kilo of itself for about eight weeks and I was fully prepared to call it a wall. Then a scheduled DEXA scan came back and told a completely…
Six orders from JEEP over about fourteen months. Guangzhou to Manchester every time. Nothing has gone wrong. Not one thing. Which is genuinely making me nervous,…
Quick one. Canada here. telehealth works very differently where I live than in the threads that dominate the front page, and I keep seeing people confidently given…
This is the experiment I have wanted to run for about a year and nobody had bothered. Stock Batch Service Claimed Result EU warehouse GY-2604W Janoshik 98.0% 97.4%…
503B. That is the whole post, but I will justify it. Everything else people worry about in c/t2dglp1 is downstream of it. Titration speed, reflux, the endless dose…
Trying to settle this properly because the thread from last year went in circles. The claim: dose history matters. The counter-claim: it is measurement error. Both…
Confession thread, sort of. I went from 1.7mg to 0.25mg much faster than I should have because the scale had stalled and I got impatient. The stall broke about 5 weeks…
Week 74 update. 10kg down from the start, early fullness basically gone since about week 31. Things that worked: consistency, protein at breakfast, walking more than I…