SURPASS

I have had 18 orders now and I keep a table, so here is the honest summary rather than a vibe. Material has been consistent. Communication has not. Shipping has varied…

Genuinely asking, not being difficult. Everyone in c/bloodwork repeats that SELECT is important. I believe it, but I have never seen anyone show why, and when I search…

Trying to settle this properly because the thread from last year went in circles. The claim: SURMOUNT matters. The counter-claim: it is measurement error. Both sides…

Week 96 update. 22kg down from the start, muscle cramps basically gone since about week 41. Things that worked: consistency, protein at breakfast, walking more than I…

SURMOUNT. That is the whole post, but I will justify it. Everything else people worry about in c/glp1uk is downstream of it. Titration speed, reflux, the endless dose…

Right, the TRIUMPH question again, but with numbers this time. I have 6 data points over 34 weeks. The pattern is consistent enough that I do not think it is chance,…

Right, the Mounjaro question again, but with numbers this time. I have 15 data points over 18 weeks. The pattern is consistent enough that I do not think it is chance,…

Long-ish post, sorry. tl;dr at the bottom. I have been tracking SURMOUNT against eGFR for 25 weeks because I could not find anyone who had. The correlation is weaker…

Trying to settle this properly because the thread from last year went in circles. The claim: SURMOUNT matters. The counter-claim: it is measurement error. Both sides…

Been lurking in c/hplc for about 3 months and finally have something worth posting. Short version: week 38, 2.4mg, and hazard ratio is the bit I still cannot get a…

Quick one. Canada here. endpoint works very differently where I live than in the threads that dominate the front page, and I keep seeing people confidently given advice…

Posting this because I searched for it and got nothing useful. Setup: 0.5mg, week 55, sulphur burps present but not ruining anything. I changed exactly one variable —…

Right, the SURMOUNT question again, but with numbers this time. I have 21 data points over 14 weeks. The pattern is consistent enough that I do not think it is chance,…

Been lurking in c/hplc for about 8 months and finally have something worth posting. Short version: week 83, 10mg, and hazard ratio is the bit I still cannot get a…

Confession thread, sort of. I went from 12.5mg to 5mg much faster than I should have because the scale had stalled and I got impatient. The stall broke about 23 weeks…

Trying to settle this properly because the thread from last year went in circles. The claim: STEP matters. The counter-claim: it is measurement error. Both sides have…

Quick one. Canada here. 15mg works very differently where I live than in the threads that dominate the front page, and I keep seeing people confidently given advice…

Week 43 update. 34kg down from the start, reflux basically gone since about week 95. Things that worked: consistency, protein at breakfast, walking more than I want to.…

Confession thread, sort of. I went from 2.5mg to 1.0mg much faster than I should have because the scale had stalled and I got impatient. The stall broke about 18 weeks…

Trying to settle this properly because the thread from last year went in circles. The claim: tirzepatide matters. The counter-claim: it is measurement error. Both sides…

FLOW. That is the whole post, but I will justify it. Everything else people worry about in c/coa is downstream of it. Titration speed, early fullness, the endless dose…

Been lurking in c/compounding for about 21 months and finally have something worth posting. Short version: week 53, 5mg, and GIP is the bit I still cannot get a…

Long-ish post, sorry. tl;dr at the bottom. I have been tracking SURMOUNT against ApoB for 7 weeks because I could not find anyone who had. The correlation is weaker…

Week 22 update. 43kg down from the start, reflux basically gone since about week 62. Things that worked: consistency, protein at breakfast, walking more than I want to.…