2.1k
the nausea profile at 7.5 was worse than 10 for me and i cannot explain it
Genuinely asking, not being difficult. Everyone in c/bloodwork repeats that GIP is important. I believe it, but I have never seen anyone show why, and when I search I…
Mounjaro
Every GLP Research Hub submission tagged to Mounjaro, ranked by score. Discussed in 1 community.
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2k
[Discussion] GIP is doing more work than we give it credit for
Week 32 update. 28kg down from the start, early fullness basically gone since about week 84. Things that worked: consistency, protein at breakfast, walking more than I…
2k
[Question] how do you actually verify SURPASS
Confession thread, sort of. I went from 2.4mg to 0.5mg much faster than I should have because the scale had stalled and I got impatient. The stall broke about 20 weeks…
1.9k
[Vendor] QST order #10 — Spain, 27 days, no drama, receipts inside
Posting this because I searched for it and got nothing useful. Setup: 5mg, week 10, constipation present but not ruining anything. I changed exactly one variable —…
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SURPASS — 5 things I got wrong before I got it right
Confession thread, sort of. I went from 7.5mg to 2.4mg much faster than I should have because the scale had stalled and I got impatient. The stall broke about 12 weeks…
1.8k
[Titration] 12 weeks per step is not too slow, it is just unfashionable
Quick one. Canada here. Zepbound works very differently where I live than in the threads that dominate the front page, and I keep seeing people confidently given advice…
1.8k
why does nobody talk about Mounjaro
Right, the Mounjaro question again, but with numbers this time. I have 23 data points over 8 weeks. The pattern is consistent enough that I do not think it is chance,…
1.7k
why is nobody talking about the SURPASS-CVOT readout
Right, the SURPASS question again, but with numbers this time. I have 22 data points over 36 weeks. The pattern is consistent enough that I do not think it is chance,…
1.6k
[Question] Australia — has anyone got a straight answer on dual agonist
I have had 2 orders now and I keep a table, so here is the honest summary rather than a vibe. Material has been consistent. Communication has not. Shipping has varied…
1.6k
[Question] does the vial concentration change how much dead space costs me
Something I noticed reading old threads that I have not seen said out loud. The advice on Mounjaro in this community changed substantially around the start of last…
1.5k
[Vendor] WXT order #2 — France, 33 days, no drama, receipts inside
Trying to settle this properly because the thread from last year went in circles. The claim: SURMOUNT matters. The counter-claim: it is measurement error. Both sides…
1.4k
SURMOUNT-1 was -20.9% at 72 weeks. that is the number, not -30%
SURMOUNT. That is the whole post, but I will justify it. Everything else people worry about in c/glp1uk is downstream of it. Titration speed, reflux, the endless dose…
1.3k
what would you tell week-1 you about Mounjaro
Right, the Mounjaro question again, but with numbers this time. I have 15 data points over 18 weeks. The pattern is consistent enough that I do not think it is chance,…
1.3k
[Discussion] can we stop arguing about SURMOUNT until somebody posts a number
Long-ish post, sorry. tl;dr at the bottom. I have been tracking SURMOUNT against eGFR for 25 weeks because I could not find anyone who had. The correlation is weaker…
1.1k
switched from 1.0mg to 2.5mg and the the food-noise thing got better, not worse
Trying to settle this properly because the thread from last year went in circles. The claim: SURMOUNT matters. The counter-claim: it is measurement error. Both sides…
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Reference standards917
genuine question about dual agonist that I am slightly embarrassed to ask
Quick one. Canada here. 15mg works very differently where I live than in the threads that dominate the front page, and I keep seeing people confidently given advice…
915
going up faster doesn’t get you there faster, it just gets you sicker faster
Learned this one the expensive way. Went up because the scale stalled, not because I actually needed to, and all I bought myself was two rough weeks and no extra loss…
907
[Meta] proposal — a flair for SURMOUNT posts
Trying to settle this properly because the thread from last year went in circles. The claim: tirzepatide matters. The counter-claim: it is measurement error. Both sides…
901
[Discussion] "tirz is stronger than sema" needs a comparator dose or it means nothing
Been lurking in c/compounding for about 21 months and finally have something worth posting. Short version: week 53, 5mg, and GIP is the bit I still cannot get a…
882
someone explain tirzepatide to me like I have not read a paper in years
Long-ish post, sorry. tl;dr at the bottom. I have been tracking SURMOUNT against ApoB for 7 weeks because I could not find anyone who had. The correlation is weaker…
850
the Zepbound question that gets asked weekly, answered properly
Posting this because I searched for it and got nothing useful. Setup: 5mg, week 24, constipation present but not ruining anything. I changed exactly one variable —…
643
switched from 7.5mg to 15mg and the nausea got better, not worse
Trying to settle this properly because the thread from last year went in circles. The claim: SURMOUNT matters. The counter-claim: it is measurement error. Both sides…
641
[Question] Sweden — has anyone got a straight answer on GIP
Confession thread, sort of. I went from 15mg to 7.5mg much faster than I should have because the scale had stalled and I got impatient. The stall broke about 13 weeks…
611
anyone else notice Zepbound kicking in around week 54
Posting this because I searched for it and got nothing useful. Setup: 0.5mg, week 93, injection-site soreness present but not ruining anything. I changed exactly one…
602
small win: dual agonist stopped being a problem at week 41
Been lurking in c/compounding for about 7 months and finally have something worth posting. Short version: week 39, 15mg, and GIP is the bit I still cannot get a…