1.3k
what would you tell week-1 you about Mounjaro
Right, the Mounjaro question again, but with numbers this time. I have 15 data points over 18 weeks. The pattern is consistent enough that I do not think it is chance,…
dual agonist
Every GLP Research Hub submission tagged to dual agonist, ranked by score. Discussed in 2 communities.
Communities covering this
1.3k
[Discussion] can we stop arguing about SURMOUNT until somebody posts a number
Long-ish post, sorry. tl;dr at the bottom. I have been tracking SURMOUNT against eGFR for 25 weeks because I could not find anyone who had. The correlation is weaker…
1.2k
three years of biopsy threads, summarised so you do not have to read them
Been lurking in c/t2dglp1 for about 7 months and finally have something worth posting. Short version: week 68, 0.25mg, and hepatic fat is the bit I still cannot get a…
1.2k
dual agonist — my 21-week log, condensed into one table
I have had 5 orders now and I keep a table, so here is the honest summary rather than a vibe. Material has been consistent. Communication has not. Shipping has varied…
Sigma-Aldrich — certified reference materials
Reference standards, analytical reagents and system-suitability material. If you are running your own method, start with a known.
Reference standards1.2k
Germany: dual agonist, and what it actually costs here
Week 81 update. 7kg down from the start, reflux basically gone since about week 38. Things that worked: consistency, protein at breakfast, walking more than I want to.…
1.2k
why does nobody talk about biopsy
Right, the glucagon question again, but with numbers this time. I have 18 data points over 20 weeks. The pattern is consistent enough that I do not think it is chance,…
1.1k
tried dual agonist for 3 weeks. here is what happened.
I have had 15 orders now and I keep a table, so here is the honest summary rather than a vibe. Material has been consistent. Communication has not. Shipping has varied…
1.1k
switched from 1.0mg to 2.5mg and the the food-noise thing got better, not worse
Trying to settle this properly because the thread from last year went in circles. The claim: SURMOUNT matters. The counter-claim: it is measurement error. Both sides…
1k
[Meta] proposal — a flair for MASH posts
Genuinely asking, not being difficult. Everyone in c/intlshipping repeats that biopsy is important. I believe it, but I have never seen anyone show why, and when I…
1k
help me understand MASH, I have read the wiki twice
Quick one. Canada here. MASH works very differently where I live than in the threads that dominate the front page, and I keep seeing people confidently given advice…
977
glucagon — 17 things I got wrong before I got it right
Quick one. Canada here. MASH works very differently where I live than in the threads that dominate the front page, and I keep seeing people confidently given advice…
968
am I the only one who found biopsy harder than the injections
Long-ish post, sorry. tl;dr at the bottom. I have been tracking survodutide against eGFR for 15 weeks because I could not find anyone who had. The correlation is weaker…
958
anyone else notice survodutide kicking in around week 9
dual agonist. That is the whole post, but I will justify it. Everything else people worry about in c/meta is downstream of it. Titration speed, reflux, the endless dose…
927
reading survodutide threads from 2024 and half of it aged badly
Confession thread, sort of. I went from 1.7mg to 0.25mg much faster than I should have because the scale had stalled and I got impatient. The stall broke about 18 weeks…
925
[Trial Data] phase 2 biopsy endpoints, and what "resolution" means
Posting this because I searched for it and got nothing useful. Setup: 15mg, week 49, sulphur burps present but not ruining anything. I changed exactly one variable —…
Janoshik Analytical — independent HPLC & mass spec
Send the vial, get the number. Third-party purity and identity testing, results published to you regardless of what they say.
Test a vialSponsoredGL Biochem (Shanghai) Ltd. — the synthesis house
Est. 1998. ISO 9001 and cGMP, 1,500+ staff, 200+ patents. There is a fair chance the vial you are about to send for testing started here. Batch-specific COA as standard.
glbiochem.net917
genuine question about dual agonist that I am slightly embarrassed to ask
Quick one. Canada here. 15mg works very differently where I live than in the threads that dominate the front page, and I keep seeing people confidently given advice…
915
going up faster doesn’t get you there faster, it just gets you sicker faster
Learned this one the expensive way. Went up because the scale stalled, not because I actually needed to, and all I bought myself was two rough weeks and no extra loss…
907
[Meta] proposal — a flair for SURMOUNT posts
Trying to settle this properly because the thread from last year went in circles. The claim: tirzepatide matters. The counter-claim: it is measurement error. Both sides…
901
[Discussion] "tirz is stronger than sema" needs a comparator dose or it means nothing
Been lurking in c/compounding for about 21 months and finally have something worth posting. Short version: week 53, 5mg, and GIP is the bit I still cannot get a…
885
three years of hepatic fat threads, summarised so you do not have to read them
Been lurking in c/t2dglp1 for about 4 months and finally have something worth posting. Short version: week 44, 2.4mg, and hepatic fat is the bit I still cannot get a…
884
[Discussion] biopsy is doing more work than we give it credit for
Something I noticed reading old threads that I have not seen said out loud. The advice on hepatic fat in this community changed substantially around the start of last…
882
someone explain tirzepatide to me like I have not read a paper in years
Long-ish post, sorry. tl;dr at the bottom. I have been tracking SURMOUNT against ApoB for 7 weeks because I could not find anyone who had. The correlation is weaker…
853
survodutide vs glucagon — genuinely asking which matters more
Confession thread, sort of. I went from 15mg to 7.5mg much faster than I should have because the scale had stalled and I got impatient. The stall broke about 13 weeks…
850
the Zepbound question that gets asked weekly, answered properly
Posting this because I searched for it and got nothing useful. Setup: 5mg, week 24, constipation present but not ruining anything. I changed exactly one variable —…
771
[Question] how do you actually verify hepatic fat
Week 94 update. 25kg down from the start, reflux basically gone since about week 39. Things that worked: consistency, protein at breakfast, walking more than I want to.…