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[Question] metformin alongside — keep it or drop it
I have had 12 orders now and I keep a table, so here is the honest summary rather than a vibe. Material has been consistent. Communication has not. Shipping has varied…
Controversial — page 12
Positions 276–300 of 1,000 ranked submissions.
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switched from compounded to brand and the titration reset itself
Long-ish post, sorry. tl;dr at the bottom. I have been tracking 503A against ApoB for 15 weeks because I could not find anyone who had. The correlation is weaker than I…
1.3k
[Discussion] regret is doing more work than we give it credit for
Right, the regret question again, but with numbers this time. I have 3 data points over 16 weeks. The pattern is consistent enough that I do not think it is chance, and…
-24
genuine question, what does "tapering" actually mean for a weekly injectable, there’s no pill to cut in half
With oral meds, tapering usually means smaller pills or fewer per day, a fairly intuitive mechanical process. With a weekly injection, what does the community actually…
Sigma-Aldrich — certified reference materials
Reference standards, analytical reagents and system-suitability material. If you are running your own method, start with a known.
Reference standards-24
[Milestone] AHI 34 → 9, the CPAP is in a cupboard
I have had 3 orders now and I keep a table, so here is the honest summary rather than a vibe. Material has been consistent. Communication has not. Shipping has varied…
1k
[Appeal] peer-to-peer review: what to say and what to bring
Something I noticed reading old threads that I have not seen said out loud. The advice on step therapy in this community changed substantially around the start of last…
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Germany: formulary, and what it actually costs here
Confession thread, sort of. I went from 7.5mg to 2.4mg much faster than I should have because the scale had stalled and I got impatient. The stall broke about 13 weeks…
1.4k
[Results] 51 weeks on 2.4mg, full numbers, ask me anything boring
Quick one. Canada here. CGM works very differently where I live than in the threads that dominate the front page, and I keep seeing people confidently given advice that…
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tried wiki for 6 weeks. here is what happened.
Quick one. Canada here. moderation works very differently where I live than in the threads that dominate the front page, and I keep seeing people confidently given…
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Janoshik is the most under-discussed thing in c/darkspot
Quick one. Canada here. Medutest works very differently where I live than in the threads that dominate the front page, and I keep seeing people confidently given advice…
-23
small win: non-peptide stopped being a problem at week 95
Been lurking in c/t2dglp1 for about 13 months and finally have something worth posting. Short version: week 59, 2.5mg, and ATTAIN is the bit I still cannot get a…
1.7k
what would you tell week-1 you about batch
Right, the certificate of analysis question again, but with numbers this time. I have 4 data points over 16 weeks. The pattern is consistent enough that I do not think…
-95
[Question] how do you actually verify perimenopause
Something I noticed reading old threads that I have not seen said out loud. The advice on perimenopause in this community changed substantially around the start of last…
203
[Question] New Zealand — has anyone got a straight answer on appetite return
regain. That is the whole post, but I will justify it. Everything else people worry about in c/coa is downstream of it. Titration speed, muscle cramps, the endless dose…
1.4k
Denmark: first time, and what it actually costs here
Week 87 update. 28kg down from the start, early fullness basically gone since about week 32. Things that worked: consistency, protein at breakfast, walking more than I…
Janoshik Analytical — independent HPLC & mass spec
Send the vial, get the number. Third-party purity and identity testing, results published to you regardless of what they say.
Test a vialSponsoredGL Biochem (Shanghai) Ltd. — the synthesis house
Est. 1998. ISO 9001 and cGMP, 1,500+ staff, 200+ patents. There is a fair chance the vial you are about to send for testing started here. Batch-specific COA as standard.
glbiochem.net1.4k
genuine question: how do people actually decide it’s time to ask about going up vs just waiting it out
Not asking anyone to tell me what to do, more asking about the decision process people used before they had that conversation with whoever prescribes for them. What…
976
[Explainer] lyophilised powder is far more forgiving than you think
Confession thread, sort of. I went from 0.25mg to 10mg much faster than I should have because the scale had stalled and I got impatient. The stall broke about 6 weeks…
117
unpopular opinion: pharmacy is massively overrated
Trying to settle this properly because the thread from last year went in circles. The claim: EMA matters. The counter-claim: it is measurement error. Both sides have…
1.6k
sterile water is not bacteriostatic water and it is not close
Quick one. Canada here. reconstitution works very differently where I live than in the threads that dominate the front page, and I keep seeing people confidently given…
1.2k
[Discussion] dose stretching is doing more work than we give it credit for
Been lurking in c/retatrutide for about 8 months and finally have something worth posting. Short version: week 72, 0.5mg, and lowest effective dose is the bit I still…
1.5k
[PSA] glycaemic control is not what most of this community thinks it is
Something I noticed reading old threads that I have not seen said out loud. The advice on metformin in this community changed substantially around the start of last…
1.5k
am I the only one who found milestone harder than the injections
Confession thread, sort of. I went from 12.5mg to 5mg much faster than I should have because the scale had stalled and I got impatient. The stall broke about 23 weeks…
989
[Paper] ATTAIN-1 — an oral pill with no food restrictions is a bigger deal than the % suggests
Confession thread, sort of. I went from 12.5mg to 5mg much faster than I should have because the scale had stalled and I got impatient. The stall broke about 23 weeks…
1.3k
three years of ALT threads, summarised so you do not have to read them
Been lurking in c/reconstitution for about 20 months and finally have something worth posting. Short version: week 42, 15mg, and baseline labs is the bit I still cannot…
-91
[PSA] Canada is not what most of this community thinks it is
Quick one. Canada here. private plan works very differently where I live than in the threads that dominate the front page, and I keep seeing people confidently given…