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c/trialwatch·submitted 4 days ago by u/britta_boateng

[Stats] relative risk reduction sells papers, absolute risk reduction makes decisions

Statsbranch of 7 comments

Genuinely asking, not being difficult. Everyone in c/compounding repeats that hazard ratio is important. I believe it, but I have never seen anyone show why, and when I search I get 6 threads of people agreeing with each other. Is there a paper? Is there a measurement? Or is this one of those things that is true…

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7 comments, started 2 days ago
u/oskar_ibarra71 points·2 days ago
fair enough
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u/week_one_wanda56 points·2 days ago

Strongly agree. Phase 2 is investigational, not conclusive.

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u/plateau_patrol27 points·2 days ago

the relative risk reduction in headlines is not the whole story

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u/ines_castellanos43 points·2 days ago

Edit to your parent would help — the concentration you quoted assumes one scenario and you have written another above it.

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u/pancreatitis_scare20 points·2 days ago

Yeah, absolute numbers matter more than the press release.

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u/joaquin_trevino14 points·2 days ago

Yeah, absolute numbers matter more than the press release.

Adding to this: SURMOUNT is doing more work than the comment implies.

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u/injection_site_iris9 points·2 days ago

What was the dropout rate?

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