does SELECT actually matter or is it forum lore at this point
Asking properly rather than in a comment on somebody else’s thread: does SELECT actually matter or is it forum lore at this point. Compared myself to a trial mean for about six months before realising the trial arm had dietitian contact every fortnight. On means, which this board treats as targets and which are…
Intention-to-treat analyses everybody randomised regardless of what they did afterwards. Completer analyses only those who finished. The second is systematically more flattering and both are legitimate if labelled.
What did the confidence interval look like?
The registered protocol is public. Comparing the registered primary endpoint with the reported one is a two-minute check and it is how outcome switching gets caught.
Do you have the publication or the press release?
Yes — the interval is the finding. A point estimate with a wide interval is a hypothesis in a nice font.
Intention-to-treat analyses everybody randomised regardless of what they did afterwards.
Disagreeing with this line: that is a relative reduction and the absolute numbers are considerably less dramatic.
What was the discontinuation rate?
What was the discontinuation rate?
Adding the check nobody runs — the registered protocol is public and takes two minutes to compare.
Correction: SURMOUNT is the obesity programme and SURPASS is the diabetes one. The figure you quoted belongs to the other one.