[Question] endpoint — what am I missing here
endpoint — what am I missing here. I would rather ask a basic question now than get this wrong quietly for two months. Spent an evening with the appendix tables and found the subgroup detail that the entire thread had been speculating about. Quoted a figure here confidently, got asked whether it was ITT, went and…
A confidence interval is the range of effects compatible with the data. Two trials with overlapping intervals have not disagreed, whatever their point estimates look like next to each other.
Relative risk reduction without the baseline rate is uninterpretable. A large relative reduction on a small absolute risk is a small absolute benefit.
Push back: an open-label extension tells you about the people who stayed. That is a different question.
Push back: an open-label extension tells you about the people who stayed.
anders_vermeulen is right about the programme names. They are different populations with different endpoints.
Agreed. Half the arguments on this site are two people quoting different trials at each other without noticing.
Small fix — that was the cardiovascular outcomes trial, so weight was a secondary endpoint and the population was different.