[Discussion] we are measuring Mounjaro at the wrong time and calling it noise
we are measuring Mounjaro at the wrong time and calling it noise — a position I have arrived at slowly and would like tested. On comparing yourself with the trial number. SURMOUNT-1 reported roughly 21% mean body weight change at 72 weeks on the highest arm. Three things get dropped every time that figure is quoted…
SURMOUNT-1 ran 72 weeks with the top arm around 21% mean body weight change. SURPASS is the diabetes programme and reports glycaemic endpoints, so quoting the two interchangeably is a category error.
Which week did the appetite change actually land for you?
a lot of people plateau nicely at 10mg and never need 15
the food noise profile is genuinely gentler than people expect coming from sema
Careful with "everyone tolerates it better". The people it did not suit stop posting, which makes this board look calmer than the drug is.
Research-use-only material is not approved for human use. Anything in this thread about how a research vial "should" titrate is a discussion about chemistry, not a plan.
zepbound and mounjaro are the same compound with different labels
Not sure that follows. You went up a step and changed your training in the same fortnight.