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c/tirzepatide·posted 1 year ago by u/neha_falk

[Question] Zepbound — what am I missing here

Question Well Actually ×9

Zepbound — what am I missing here. I would rather ask a basic question now than get this wrong quietly for two months.

Held 7.5 for five months. Everyone kept asking when I was going to 10. The answer was never, because 7.5 was working.

Came off sema and onto tirz with a two-week gap. The first month was flat and I assumed I had made a mistake. Month two it moved.

Sulphur burps for the first eight days after each step, then nothing. Predictable enough that I planned my week around it.

Sceptical readings welcome. The confident ones are the ones I distrust.

423 up / 139 down75% upvoted15 commentsid sv0zr214 Jan 2025

15 comments

7 in this archive, depth 3

best — the order this archive was captured in

u/dexa_twice_yearlybody comp33 points·1 year ago

Switching from semaglutide, since three people asked in this thread alone.

There is no published dose equivalence between the two. The conversion tables that circulate are somebody’s arithmetic, not data. What people report here is that the first month after a switch is often flat, that the appetite effect feels differently shaped rather than simply stronger, and that starting at the bottom of the ladder again is the common approach.

None of that is a recommendation. It is what the threads say, and the threads are not a clinic.

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u/noor_hovland39 points·1 year ago

zepbound and mounjaro are the same compound with different labels

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[removed]17 points·1 year ago

[removed by moderator]

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u/hub_opssite staff25 points·1 year ago

Did you come to this from sema, and if so how long was the gap?

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u/mod_cold_roommod · c/coldchain30 points·1 year ago

Appetite effect for me is flat across seven days. On sema it was a wave. Same person, different molecule.

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u/titration_marshalMOD21 points·1 year ago

This is the fifth "should I go up" post today and they are all welcome — but no member here can answer it for you.

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u/incretin_ivypharmacology7 points·1 year ago

Not sure that follows. You went up a step and changed your training in the same fortnight.

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About c/tirzepatide

Tirzepatide-specific discussion: the dual-agonist pharmacology, the 2.5 → 15mg ladder, the appetite profile people describe as different from semaglutide, and the SURMOUNT/SURPASS trial programme. Comparisons with semaglutide are welcome as long as they are specific about dose equivalence being unknown.

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