[Question] is 93.7% actually fine or am I being sold a rounding error
Right: is 93.7% actually fine or am I being sold a rounding error. I paid for this one myself, nobody sent me anything, and the receipts are in the comments.
The numbers the title promised, since a headline without them is worthless: 93.7%. Everything below is context for those.
Vials and pens carry the same molecule; what differs is fill volume, device tolerance and whether you are doing your own arithmetic. Neither is inherently more accurate.
Research-use-only material is not approved for human use. Anything in this thread about how a research vial "should" titrate is a discussion about chemistry, not a plan.
Research-use-only material is not approved for human use and nothing here should be read as a recommendation to use it.
best — the order this archive was captured in
The four-week interval in the label is a minimum. Nothing about the pharmacology requires you to step on schedule, and the trials stepped on a calendar because trials have to.
pens and vials are the same molecule, the price is the difference
hold the dose that works, the ladder is not a leaderboard
Are you comparing yourself with the trial mean or with the people who post the most?
Small fix: SURMOUNT is the obesity programme, SURPASS is the type-2 programme. They are different endpoints and the numbers do not transfer.
That percentage is body weight change, not body fat. Different measurement, and the distinction gets lost every time.
I would separate the two claims. That the GIP arm exists is uncontroversial; that it explains your fatigue pattern is a guess.
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2.5mg is a four-week starting dose, not a maintenance dose. Worth being precise since people search these threads.
the trials titrated on a calendar, real people titrate on symptoms
Pen or vial? The step sizes available differ and it changes this answer.
Went 10 to 12.5 on the calendar and had the worst fortnight of the whole run. Dropped back to 10 and everything settled.
Went 10 to 12.5 on the calendar and had the worst fortnight of the whole run.
This. The step interval is a floor, and reading it as a timetable is the most expensive mistake in the thread.
sulphur burps are the signature complaint and they are not dangerous
the early fullness profile is genuinely gentler than people expect coming from sema
Yes — 10mg being a genuine landing place for a lot of people is underrated. There is no medal for 15.
Yes — 10mg being a genuine landing place for a lot of people is underrated.
Agreed, with one qualifier: that is the mean of the top arm and the spread around it was enormous.
Push back: "gentler than sema" is a population statement. Plenty of people on this board have the opposite experience and they are not doing it wrong.
Does nausea follow the day after the shot, or is it spread across the week?
stepping every four weeks is a ceiling on speed, not a schedule you must hit
Appetite effect for me is flat across seven days. On sema it was a wave. Same person, different molecule.
2.5 is the starter dose and it is not meant to be the dose that works
the appetite effect is blunter than sema, in a good way, most weeks
a lot of people plateau nicely at 10mg and never need 15
Right. And the sema-to-tirz "conversion" people post is invented. There is no published equivalence.
Weekly dosing again, half-life in the same neighbourhood as sema, so a step change takes about a month to reach steady state. Judging a new step at day five is judging noise.
Weekly dosing again, half-life in the same neighbourhood as sema, so a step change takes about a month to reach steady state.
fatima_wojcik is right that the two molecules are not interchangeable. There is no published conversion and the ones circulating are invented.
What is the waist doing? That is usually the number still moving during a scale stall.
Left up, flair changed to Discussion. It is an opinion post and that is fine as long as it is labelled.
Careful with "everyone tolerates it better". The people it did not suit stop posting, which makes this board look calmer than the drug is.
- 1The four-week interval in the label is a minimum. Nothing about the…11 comments in this branch · started by u/aurel_lindqvist
- 2the early fullness profile is genuinely gentler than people expect coming…6 comments in this branch · started by u/britt_okwuosa