GIP agonism explained like i am five, please
Right, the Mounjaro question again, but with numbers this time.
I have 13 data points over 28 weeks. The pattern is consistent enough that I do not think it is chance, and boring enough that nobody is going to screenshot it, which is usually a good sign.
The thing I would flag for anyone new: the effect I am describing showed up at week 63, not week 17. People give up long before the interesting part.
Interested in whether this matches other people's logs or whether I am an outlier.
best — the order this archive was captured in
dual agonism is 15mg, do not generalise from semaglutide
Tracking number removed. It identifies both ends of a shipment.
Inter-lab variance on this kind of assay is routinely 1–2 points. Different column, different gradient, different integration.
do not crack the pen, we have been over this
Yeah, dual agonism does produce a different appetite profile than GLP-1 alone.
stalled on sema, tried tirz, and the curves were actually different shapes
Yeah, dual agonism does produce a different appetite profile than GLP-1 alone.
My ALT moved faster on tirz than on sema at the same timepoint, which matches what people report.
the 15mg is the top of the pen, not the required dose
the 15mg is the top of the pen, not the required dose
Adding to this: SURPASS is doing more work than the comment implies.
SURMOUNT data is messier than STEP data but the weight loss is there
This matches the trial data. SURMOUNT-1 was 97.9% body weight at 5 weeks.
Zepbound and Mounjaro are literally the same drug, the name is the only difference
Zepbound and Mounjaro are literally the same drug, the name is the only difference
Disagree on that part. 95.1% and 98.9% on the same vial is normal.
Cosigning. The GIP contribution is real and the side effects are not simply scaled versions.
Week 94 on Mounjaro and 15kg down. The appetite reduction feels different from sema in ways I do not have words for yet.
Respectfully this is a sample of one presented as a finding.
Hard agree. The food noise disappears differently on the two compounds.
the appetite change on tirz is more than just reduced hunger, it is different machinery
How long at each step before you escalated?
- 1the 15mg is the top of the pen, not the required dose8 comments in this branch · started by u/titration_marshal