[Results] 63 weeks on 5mg, full numbers, ask me anything boring
Reporting in. 63 weeks on 5mg, full numbers, ask me anything boring.
63 weeks and 5mg — those are the numbers, and they are the ones I am willing to defend.
Came off sema and onto tirz with a two-week gap. The first month was flat and I assumed I had made a mistake. Month two it moved.
Sulphur burps for the first eight days after each step, then nothing. Predictable enough that I planned my week around it.
Research-use-only material is not approved for human use and nothing here should be read as a recommendation to use it.
best — the order this archive was captured in
This is the fifth "should I go up" post today and they are all welcome — but no member here can answer it for you.
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The 21% figure is a 72-week mean on the highest arm. Quoting it as what someone should expect by week 43 is not a fair reading.
pens and vials are the same molecule, the price is the difference
pens and vials are the same molecule, the price is the difference
Not sure about this bit. The GIP arm being real does not tell you that it is what caused your particular week.
I would separate the two claims. That the GIP arm exists is uncontroversial; that it explains your sulphur burps pattern is a guess.
On comparing yourself with the trial number.
SURMOUNT-1 reported roughly 21% mean body weight change at 72 weeks on the highest arm. Three things get dropped every time that figure is quoted here. It is a mean, and the distribution around it is very wide. It is 72 weeks, which is a year and a half. And it is a trial population with trial support, which is not the same as a person with a spreadsheet.
Use it as a rough shape, not a benchmark. A 12% year is inside the ordinary range and people quit over it every week on this board.
week 8 is early to draw any conclusion at all
sulphur burps are the signature complaint and they are not dangerous
This matches mine. Milder nausea than I expected, and what there was settled inside a fortnight of each step.
It is a dual GIP and GLP-1 receptor agonist, and the GIP arm is the part that has no equivalent in the semaglutide threads. That is why the side-effect profile reads differently rather than just milder.
Pen or vial? The step sizes available differ and it changes this answer.
Agree. The GIP component is the interesting half and it barely gets discussed outside c/glp1science.
That percentage is body weight change, not body fat. Different measurement, and the distinction gets lost every time.
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