GLPHubglpresearchhub.com
Read-only archive. GLP Research Hub is a static community record — nothing here is for sale, no account is needed, and no vote you cast is counted. Why?
Single comment threadYou are looking at one branch of three years of 15mg threads, summarised so you do not have to read them — 45 comments in the full submission. View in context.
6.1k
c/tirzepatide·submitted 8 months ago by u/ignacio_vanhecke

three years of 15mg threads, summarised so you do not have to read them

Resultsbranch of 14 comments

three years of 15mg threads, summarised so you do not have to read them. It is the sort of thing everyone half-believes and nobody writes down. The numbers the title promised, since a headline without them is worthless: 15mg. Everything below is context for those. Came off sema and onto tirz with a two-week gap. The…

Read the full submission and all 45 comments →

This branch

14 comments, started 8 months ago
u/ferritin_low187 points·8 months ago

Did you come to this from sema, and if so how long was the gap?

replysharereportpermalink
u/ingrid_correia153 points·8 months ago

Which week did the appetite change actually land for you?

replysharereportpermalink
[deleted]108 points·8 months ago

[deleted]

replysharereportpermalink
u/sanne_novak91 points·8 months ago

That percentage is body weight change, not body fat. Different measurement, and the distinction gets lost every time.

replysharereportpermalink
u/quiet_moderatormod44 points·8 months ago

hold the dose that works, the ladder is not a leaderboard

replysharereportpermalink
u/tarek_lokken69 points·8 months ago

2.5 is the starter dose and it is not meant to be the dose that works

replysharereportpermalink
u/discount_math_dm-14 points·8 months ago

SURMOUNT-1 landed around 21% at 72 weeks on the top arm

replysharereportpermalink
u/copay_card_cc178 points·8 months ago

Went 10 to 12.5 on the calendar and had the worst fortnight of the whole run. Dropped back to 10 and everything settled.

replysharereportpermalink
u/ignacio_vanheckeOP83 points·8 months ago

Week 67 was the first time the scale moved after a five-week stall. I changed nothing in that window.

replysharereportpermalink
u/vito_chowdhury154 points·8 months ago

the four-week step schedule is the label, not folklore

replysharereportpermalink
u/ignacio_vanheckeOP78 points·8 months ago

Does nausea follow the day after the shot, or is it spread across the week?

replysharereportpermalink
u/bastian_eriksen63 points·8 months ago

Push back: "gentler than sema" is a population statement. Plenty of people on this board have the opposite experience and they are not doing it wrong.

replysharereportpermalink
u/dario_vermeulen22 points·8 months ago

zepbound and mounjaro are the same compound with different labels

replysharereportpermalink
u/yusuf_ramos15 points·8 months ago

Small fix: SURMOUNT is the obesity programme, SURPASS is the type-2 programme. They are different endpoints and the numbers do not transfer.

replysharereportpermalink

← back to the whole thread

About c/tirzepatide

Tirzepatide-specific discussion: the dual-agonist pharmacology, the 2.5 → 15mg ladder, the appetite profile people describe as different from semaglutide, and the SURMOUNT/SURPASS trial programme. Comparisons with semaglutide are welcome as long as they are specific about dose equivalence being unknown.

187kmembers
130submissions
Aug 2023created
submissions / month, last year
Sponsored

Sigma-Aldrich Standards

Certified reference materials for peptide identity and purity work.

sigmaaldrich.com
c/tirzepatide rules
  1. "Tirz is better than sema" needs a comparator dose or it is a vibe, not a claim.
  2. Vial-splitting and self-compounding discussion stays in c/reconstitution.
  3. No pen-cracking tutorials. Discussing that people do it is fine; instructions are not.
  4. Independent community. Nobody here sells anything, and anyone who tries is banned.
  5. Not medical advice. Describe what you did; never prescribe to a stranger.
  6. Claims need evidence. Batch numbers, dated screenshots, independent test reports, or a citation.
  7. No referral links, discount codes or affiliate URLs. Permanent ban, no appeal.
  8. No contact handles, wallet addresses or tracking numbers — they identify people.
  9. Be recognisably decent. Disagree hard, insult nobody.
Moderators
Volunteers. Unpaid, unaffiliated, and reachable through modmail only.
Before you read on

Several compounds discussed on GLP Research Hub are sold for research use only and are not approved for human use anywhere. Nothing here is medical advice and none of it is written by your clinician. If a post reads like an instruction, treat it as a description of what one stranger did.