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c/tirzepatide·submitted 6 months ago by u/customs_seizure_sid

is it normal to get food noise at week 85

Titrationbranch of 7 comments

Reporting in. is it normal to get food noise at week 85. Research-use-only material is not approved for human use. Anything in this thread about how a research vial "should" titrate is a discussion about chemistry, not a plan. SURMOUNT-1 ran 72 weeks with the top arm around 21% mean body weight change. SURPASS is the…

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7 comments, started 6 months ago
u/forest_plot_fionastats69 points·6 months ago

It is a dual GIP and GLP-1 receptor agonist, and the GIP arm is the part that has no equivalent in the semaglutide threads. That is why the side-effect profile reads differently rather than just milder.

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u/customs_seizure_sidOP25 points·6 months ago

2.5mg is a four-week starting dose, not a maintenance dose. Worth being precise since people search these threads.

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u/customs_seizure_sidOP-28 points·6 months ago

hold the dose that works, the ladder is not a leaderboard

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u/fatima_wojcik1 point·6 months ago

Cosigning the four-week thing. It is a minimum interval, and treating it as a schedule to keep up with is how people end up miserable at 12.5.

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u/customs_seizure_sidOP1 point·6 months ago

What step are you on and how long have you been there?

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u/incretin_ivyMOD38 points·6 months ago

This is the fifth "should I go up" post today and they are all welcome — but no member here can answer it for you.

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u/two_mil_or_one45 points·6 months ago

sulphur burps are the signature complaint and they are not dangerous

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About c/tirzepatide

Tirzepatide-specific discussion: the dual-agonist pharmacology, the 2.5 → 15mg ladder, the appetite profile people describe as different from semaglutide, and the SURMOUNT/SURPASS trial programme. Comparisons with semaglutide are welcome as long as they are specific about dose equivalence being unknown.

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