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c/tirzepatide·submitted 7 months ago by u/mikkel_ogunleye

[Question] Mounjaro — what am I missing here

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Asking properly rather than in a comment on somebody else’s thread: Mounjaro — what am I missing here. On comparing yourself with the trial number. SURMOUNT-1 reported roughly 21% mean body weight change at 72 weeks on the highest arm. Three things get dropped every time that figure is quoted here. It is a mean, and…

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6 comments, started 7 months ago
u/titration_marshalMOD528 points·7 months ago

Left up, flair changed to Discussion. It is an opinion post and that is fine as long as it is labelled.

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u/line_petrov418 points·7 months ago

Small fix: SURMOUNT is the obesity programme, SURPASS is the type-2 programme. They are different endpoints and the numbers do not transfer.

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[removed]275 points·6 months ago

[removed by moderator]

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u/mikkel_ogunleyeOP223 points·7 months ago

sulphur burps are the signature complaint and they are not dangerous

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u/mikkel_ogunleyeOP0 points·6 months ago

What step are you on and how long have you been there?

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About c/tirzepatide

Tirzepatide-specific discussion: the dual-agonist pharmacology, the 2.5 → 15mg ladder, the appetite profile people describe as different from semaglutide, and the SURMOUNT/SURPASS trial programme. Comparisons with semaglutide are welcome as long as they are specific about dose equivalence being unknown.

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