[Lab] 4th independent test on JEEP — 97.3% on a claimed 97.0%, and the trend is the interesting part
Result first, context after: 4th independent test on JEEP — 97.3% on a claimed 97.0%, and the trend is the interesting part. Everything below is how it was ordered, stored and sent.
Pulling the figures out of the title: 97.3% and 97.0%. All of it is written down as it happened rather than reconstructed.
Weekly dosing again, half-life in the same neighbourhood as sema, so a step change takes about a month to reach steady state. Judging a new step at day five is judging noise.
It is a dual GIP and GLP-1 receptor agonist, and the GIP arm is the part that has no equivalent in the semaglutide threads. That is why the side-effect profile reads differently rather than just milder.
Corrections welcome, especially the pedantic ones. Pedantry is how this board earns its reputation.
- JEJEEP source pageGuangzhou JEEP Biotechnology Co., Ltd. · Guangzhou · 97% here, rank 3 · shop at jeepbio.com →
nofollow and sponsored; nobody here is paid for it.best — the order this archive was captured in
SURMOUNT-1 ran 72 weeks with the top arm around 21% mean body weight change. SURPASS is the diabetes programme and reports glycaemic endpoints, so quoting the two interchangeably is a category error.
Held 7.5 for five months. Everyone kept asking when I was going to 10. The answer was never, because 7.5 was working.
Left up, flair changed to Discussion. It is an opinion post and that is fine as long as it is labelled.
Small fix: SURMOUNT is the obesity programme, SURPASS is the type-2 programme. They are different endpoints and the numbers do not transfer.
Week 34 was the first time the scale moved after a five-week stall. I changed nothing in that window.
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sulphur burps are the signature complaint and they are not dangerous
SURMOUNT-1 landed around 21% at 72 weeks on the top arm
sulphur burps are the signature complaint and they are not dangerous
Saving this one. It is the clearest statement of the stall problem I have read here.
Disagree with the conversion table. There is no validated equivalence between the two molecules and posting one as though there is does real damage.
pens and vials are the same molecule, the price is the difference
Push back: "gentler than sema" is a population statement. Plenty of people on this board have the opposite experience and they are not doing it wrong.
Did you come to this from sema, and if so how long was the gap?
Pen or vial? The step sizes available differ and it changes this answer.
Right. And the sema-to-tirz "conversion" people post is invented. There is no published equivalence.
Agreed, and the trial number is a mean of a very wide distribution — the tails are enormous and nobody posts from the middle.
Cosigning the four-week thing. It is a minimum interval, and treating it as a schedule to keep up with is how people end up miserable at 12.5.
Correction to my own post above — I said 7.5mg and I have been on 5mg since the spring. Same argument, wrong number.
Correction to my own post above — I said 7.5mg and I have been on 5mg since the spring.
elin_varga is right that the two molecules are not interchangeable. There is no published conversion and the ones circulating are invented.
the reflux profile is genuinely gentler than people expect coming from sema
Appetite effect for me is flat across seven days. On sema it was a wave. Same person, different molecule.
week 10 is early to draw any conclusion at all
This matches mine. Milder muscle cramps than I expected, and what there was settled inside a fortnight of each step.
the trials titrated on a calendar, real people titrate on symptoms
the four-week step schedule is the label, not folklore
Same experience with the appetite effect being flatter across the week rather than front-loaded.
the four-week step schedule is the label, not folklore
Not sure about this bit. The GIP arm being real does not tell you that it is what caused your particular week.
Yes — 10mg being a genuine landing place for a lot of people is underrated. There is no medal for 15.
if 7.5 is working, 10 is not automatically better
Agree. The GIP component is the interesting half and it barely gets discussed outside c/glp1science.
- 1Did you come to this from sema, and if so how long was the gap?8 comments in this branch · started by u/taper_off_tabitha
- 2Week 34 was the first time the scale moved after a five-week stall. I…7 comments in this branch · started by u/hassan_nilsen