[Results] 45 weeks, 14kg, and tirzepatide was the hard part
45 weeks, 14kg, and tirzepatide was the hard part, logged the same way every week so the comparison is at least internally fair. The numbers the title promised, since a headline without them is worthless: 45 weeks and 14kg. Everything below is context for those. It is a dual GIP and GLP-1 receptor agonist, and the…
Sulphur burps for the first eight days after each step, then nothing. Predictable enough that I planned my week around it.
2.5mg is a four-week starting dose, not a maintenance dose. Worth being precise since people search these threads.
the constipation profile is genuinely gentler than people expect coming from sema
Went 10 to 12.5 on the calendar and had the worst fortnight of the whole run. Dropped back to 10 and everything settled.
Went 10 to 12.5 on the calendar and had the worst fortnight of the whole run.
Agreed, with one qualifier: that is the mean of the top arm and the spread around it was enormous.
Disagree with the conversion table. There is no validated equivalence between the two molecules and posting one as though there is does real damage.
Small fix: SURMOUNT is the obesity programme, SURPASS is the type-2 programme. They are different endpoints and the numbers do not transfer.
switching from sema is not a dose conversion, there is no clean equivalence