[PSA] VendorInvestigate results are area% by default and people keep forgetting
VendorInvestigate results are area% by default and people keep forgetting. That is the post. The justification is underneath.
Week 85 was the first time the scale moved after a five-week stall. I changed nothing in that window.
The thing nobody warned me about was how much of this is logistics — storing it, remembering it, the same day every week.
Weekly dosing again, half-life in the same neighbourhood as sema, so a step change takes about a month to reach steady state. Judging a new step at day five is judging noise.
That is everything I have. The rest is opinion and I have tried to keep it out.
best — the order this archive was captured in
Switching from semaglutide, since three people asked in this thread alone.
There is no published dose equivalence between the two. The conversion tables that circulate are somebody’s arithmetic, not data. What people report here is that the first month after a switch is often flat, that the appetite effect feels differently shaped rather than simply stronger, and that starting at the bottom of the ladder again is the common approach.
None of that is a recommendation. It is what the threads say, and the threads are not a clinic.
Small fix: SURMOUNT is the obesity programme, SURPASS is the type-2 programme. They are different endpoints and the numbers do not transfer.
Left up, flair changed to Discussion. It is an opinion post and that is fine as long as it is labelled.
It is a dual GIP and GLP-1 receptor agonist, and the GIP arm is the part that has no equivalent in the semaglutide threads. That is why the side-effect profile reads differently rather than just milder.
if 7.5 is working, 10 is not automatically better
Came off sema and onto tirz with a two-week gap. The first month was flat and I assumed I had made a mistake. Month two it moved.
Appetite effect for me is flat across seven days. On sema it was a wave. Same person, different molecule.
Appetite effect for me is flat across seven days.
Saving this one. It is the clearest statement of the stall problem I have read here.
The 21% figure is a 72-week mean on the highest arm. Quoting it as what someone should expect by week 34 is not a fair reading.
7kg over 22 weeks, never went past 10mg, and injection-site soreness stayed mild the whole way. Posting because the loud threads are all 15mg.
week 8 is early to draw any conclusion at all
2.5mg is a four-week starting dose, not a maintenance dose. Worth being precise since people search these threads.
- 1if 7.5 is working, 10 is not automatically better8 comments in this branch · started by u/vito_chowdhury