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c/tirzepatide·submitted 2 years ago by u/mod_cold_room

[Question] how do you actually verify GIP

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Asking properly rather than in a comment on somebody else’s thread: how do you actually verify GIP. Vials and pens carry the same molecule; what differs is fill volume, device tolerance and whether you are doing your own arithmetic. Neither is inherently more accurate. Went 10 to 12.5 on the calendar and had the…

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6 comments, started 2 years ago
u/dario_stanescu170 points·2 years ago

SURMOUNT-1 ran 72 weeks with the top arm around 21% mean body weight change. SURPASS is the diabetes programme and reports glycaemic endpoints, so quoting the two interchangeably is a category error.

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u/incretin_ivyMOD85 points·2 years ago

Left up, flair changed to Discussion. It is an opinion post and that is fine as long as it is labelled.

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u/mod_cold_roomOPmod · c/coldchain48 points·2 years ago·edited

That percentage is body weight change, not body fat. Different measurement, and the distinction gets lost every time.

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[removed]62 points·2 years ago

[removed by moderator]

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About c/tirzepatide

Tirzepatide-specific discussion: the dual-agonist pharmacology, the 2.5 → 15mg ladder, the appetite profile people describe as different from semaglutide, and the SURMOUNT/SURPASS trial programme. Comparisons with semaglutide are welcome as long as they are specific about dose equivalence being unknown.

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