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c/tapering·submitted 16 days ago by u/priya_guerrero

[Discussion] restarting is not failing and we should say that louder

Discussionbranch of 10 comments

Long-ish post, sorry. tl;dr at the bottom. I have been tracking tapering against ApoB for 35 weeks because I could not find anyone who had. The correlation is weaker than I expected, which is itself mildly interesting given how confidently people link the two in here. Caveats up front: one person, one lab, one assay,…

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10 comments, started 14 days ago
u/maintenance_mode_maxMOD61 points·14 days ago

Flair changed to match the content. Read the sidebar before posting next time and we are square.

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u/lina_adebayo28 points·14 days ago

This is correct. Discontinuation data is real.

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u/preservative_free_p14 points·14 days ago

What are you comparing it against though?

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u/peptidemeter_pat8 points·13 days ago

Yeah, regain is not a failure.

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u/chain_confirm_cpayments11 points·13 days ago

no shaming people who restart

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u/priya_guerreroOP0 points·13 days ago

Came off after 51 weeks for financial reasons. Regained about a third over the following year. Back on now at a much lower dose.

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[deleted]22 points·14 days ago

[deleted]

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u/katrin_diallo7 points·13 days ago

the 8 week discontinuation arm is the data

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Stopping on purpose: dose reduction versus interval stretching, what the discontinuation arms of STEP 1 and SURMOUNT-4 actually showed about regain, appetite return timelines, and the people who came off, regained, and went back on without treating it as a failure.

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