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c/tapering·posted 1 year ago by u/anders_kuusela

[Meta] proposal — a flair for tapering posts

Question Clean Column ×4 The Quiet One ×3 Slow Clap ×2

proposal — a flair for tapering posts. Disagreement welcome, but bring a concrete alternative wording.

What the evidence says about stopping, written plainly because the framing does real damage.

Withdrawal studies across this class consistently show substantial regain after discontinuation. Appetite typically returns first, well before weight changes. This is a finding about the pharmacology of a chronic condition, in the same way that blood pressure rises again when an antihypertensive is stopped.

People on this board quit in shame over an entirely predictable result, and then avoid coming back because they have interpreted it as a personal failure. It is not. Knowing that in advance is the single most useful thing this board can offer anybody planning to stop.

Preparing to stop, as described by people here who have done it.

Write down where you are first: dose, date, weight, waist, and an honest note about how appetite feels. That page is what makes the following six months interpretable rather than a fog of impressions.

Decide in advance what you are watching for and over what period — appetite in the first month, weight over three, and a specific threshold at which you would want to revisit the decision. Have the conversation with a clinician before rather than after.

None of that is a schedule. It is a way of arriving at whatever happens next with information rather than with a vague sense of how it is going.

Why the first fortnight tells you nothing.

With a week-long half-life, exposure declines over several weeks after a final dose rather than ending with it. So the first two weeks after stopping are still a tail of the previous state, and the stability people report in that window is not evidence about the months after it.

The reports here are fairly consistent: appetite noticeably different somewhere in the second month, weight following later, and the trajectory strongly influenced by whether the habits from the losing phase survived. That is not a prediction for anybody in particular, and it is not a schedule — it is the shape of what members describe, which is the most this board can honestly offer.

Research-use-only material is not approved for human use and nothing here should be read as a recommendation to use it.

2,749 up / 143 down95% upvoted57 commentsid j92p1618 Apr 2025

57 comments

28 in this archive, depth 6

best — the order this archive was captured in

u/maintenance_mode_maxmaintenance207 points·1 year ago

Interval stretching lowers the trough concentration while keeping the dose; dose reduction lowers the level while keeping the rhythm. They are different interventions with different subjective profiles.

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u/anders_kuuselaOP299 points·1 year ago·edited

The habits are what carried it for a while. When they slipped, everything else followed, in that order.

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u/anders_kuuselaOP-22 points·1 year ago

coming back later is allowed and it is common

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u/viktor_laurent248 points·1 year ago

Disagree with the framing. Regain is the documented outcome after discontinuation; calling it a personal failure is both wrong and corrosive.

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u/ferran_krastev173 points·1 year ago

That reads as advice to stop, which is not something anyone here should be offering.

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u/viktor_kirchner39 points·1 year ago

the habits are what has to carry it afterwards

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u/zeynep_villalobos15 points·1 year ago

stopping abruptly and stopping gradually are different experiences

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u/dizzy_on_standing4 points·1 year ago

appetite comes back before the weight does

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u/marta_dziedzic18 points·1 year ago

stretching to ten days then twelve is the pattern people report

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u/rekha_teixeira5 points·1 year ago

nobody here can write you a taper schedule

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u/border_paperwork22 points·1 year ago

Nothing on this board is a taper schedule, and no member can write one for another. What can be shared is what people watched and what they observed.

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u/ilias_nakamura18 points·1 year ago

interval stretching is the most commonly described approach here

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u/quarter_dose_queenlow and slow84 points·1 year ago·edited

Push back: that is a taper schedule aimed at another member and this board does not host those.

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u/andres_restrepo63 points·1 year ago

Withdrawal studies across this class consistently show substantial regain after discontinuation, with appetite typically returning before weight changes. That is a description of the pharmacology of a chronic condition.

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u/anders_kuuselaOP48 points·1 year ago

the withdrawal data is unambiguous and it is not about willpower

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u/chidi_roos17 points·1 year ago

Appetite is the proximal effect and weight is the lagging integrated outcome, which is why watching appetite gives you an earlier and more honest signal.

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u/ferran_krastev13 points·1 year ago

Careful — interval stretching and dose reduction are different interventions and your post uses them interchangeably.

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u/zeynep_weiss7 points·1 year ago·edited

Careful — interval stretching and dose reduction are different interventions and your post uses them interchangeably.

ferran_krastev is right that regain is a documented outcome rather than a character verdict.

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u/britta_boateng4 points·1 year ago

regain is the expected outcome and framing it as failure helps nobody

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u/viktor_kirchner2 points·1 year ago

Is this a pause or a stop? They are different plans.

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u/preservative_free_p49 points·1 year ago

watch appetite, not the scale, for the first month

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u/preservative_free_p21 points·1 year ago

a fortnight of nothing is not evidence that you are fine

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u/elin_varga13 points·1 year ago

What are you planning to watch for, and over what period?

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u/chain_confirm_cpayments4 points·1 year ago

decide what you are watching for before you stop

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u/dizzy_on_standing3 points·1 year ago

Stretching the interval or reducing the dose?

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u/skip_week_sceptic40 points·1 year ago

Stopped abruptly once and gradually once. The gradual one was easier to interpret because I could see what was changing.

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u/maintenance_mode_maxMOD22 points·1 year ago

Removed the taper schedule written for another member. Describe your own experience instead.

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u/micro_bump_mick10 points·1 year ago

write down where you are before you change anything

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About c/tapering

Stopping on purpose: dose reduction versus interval stretching, what the discontinuation arms of STEP 1 and SURMOUNT-4 actually showed about regain, appetite return timelines, and the people who came off, regained, and went back on without treating it as a failure.

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