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c/tapering·posted 10 months ago by u/chidi_vermeulen

appetite return is the most under-discussed thing on this board

Question

The title is the argument: appetite return is the most under-discussed thing on this board. Here is the rest of it.

Withdrawal studies across this class consistently show substantial regain after discontinuation, with appetite typically returning before weight changes. That is a description of the pharmacology of a chronic condition.

Why the first fortnight tells you nothing.

With a week-long half-life, exposure declines over several weeks after a final dose rather than ending with it. So the first two weeks after stopping are still a tail of the previous state, and the stability people report in that window is not evidence about the months after it.

The reports here are fairly consistent: appetite noticeably different somewhere in the second month, weight following later, and the trajectory strongly influenced by whether the habits from the losing phase survived. That is not a prediction for anybody in particular, and it is not a schedule — it is the shape of what members describe, which is the most this board can honestly offer.

Preparing to stop, as described by people here who have done it.

Write down where you are first: dose, date, weight, waist, and an honest note about how appetite feels. That page is what makes the following six months interpretable rather than a fog of impressions.

Decide in advance what you are watching for and over what period — appetite in the first month, weight over three, and a specific threshold at which you would want to revisit the decision. Have the conversation with a clinician before rather than after.

None of that is a schedule. It is a way of arriving at whatever happens next with information rather than with a vague sense of how it is going.

Would rather be corrected in public than confident in private.

42 up / 64 down40% upvoted9 commentsid hl88db3 Sep 2025

9 comments

9 in this archive, depth 3

best — the order this archive was captured in

u/taper_off_tabithaMOD6 points·10 months ago

Left up. It is honest about the reason for stopping and about the timeline.

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u/fabio_lehtinen5 points·10 months ago

What are you planning to watch for, and over what period?

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u/honest_syringe_20253 points·10 months ago

the withdrawal data is unambiguous and it is not about willpower

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u/valeria_girard4 points·10 months ago

A written baseline — dose, date, weight, waist, and how appetite feels — taken before any change is what makes the following months interpretable rather than a series of impressions.

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u/chidi_vermeulenOP2 points·10 months ago

A written baseline — dose, date, weight, waist, and how appetite feels — taken before any change is what makes the following months interpretable rath

valeria_girard is right that regain is a documented outcome rather than a character verdict.

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u/ferran_krastev1 point·10 months ago

the habits are what has to carry it afterwards

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u/viktor_kirchner3 points·10 months ago

The habits are what carried it for a while. When they slipped, everything else followed, in that order.

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u/camila_marchand-30 points·10 months ago

nobody here can write you a taper schedule

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u/neha_krastev-44 points·10 months ago

decide what you are watching for before you stop

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About c/tapering

Stopping on purpose: dose reduction versus interval stretching, what the discontinuation arms of STEP 1 and SURMOUNT-4 actually showed about regain, appetite return timelines, and the people who came off, regained, and went back on without treating it as a failure.

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