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c/tapering·posted 1 year ago by u/piotr_bruun

appetite return — my 20-week log, condensed into one table

Question Clean Column ×7

Thinking out loud about this: appetite return — my 20-week log, condensed into one table.

Went back on after eight months away. Nobody here made me feel bad about it, which mattered more than I expected.

Had the conversation with a clinician before stopping rather than after. Considerably easier that way round.

Stopped abruptly once and gradually once. The gradual one was easier to interpret because I could see what was changing.

Sceptical readings welcome. The confident ones are the ones I distrust.

924 up / 275 down77% upvoted16 commentsid g73wwi18 Feb 2025

16 comments

14 in this archive, depth 4

best — the order this archive was captured in

u/controversial_only88 points·1 year ago

Why the first fortnight tells you nothing.

With a week-long half-life, exposure declines over several weeks after a final dose rather than ending with it. So the first two weeks after stopping are still a tail of the previous state, and the stability people report in that window is not evidence about the months after it.

The reports here are fairly consistent: appetite noticeably different somewhere in the second month, weight following later, and the trajectory strongly influenced by whether the habits from the losing phase survived. That is not a prediction for anybody in particular, and it is not a schedule — it is the shape of what members describe, which is the most this board can honestly offer.

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u/arne_amankwah23 points·1 year ago

Stretching the interval or reducing the dose?

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u/coa_janitormod · c/coa76 points·1 year ago

Have you had the conversation with a clinician yet?

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u/hana_lehtinen34 points·1 year ago

Have you had the conversation with a clinician yet?

Agreed — and the exposure lag means the first fortnight tells you almost nothing.

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u/laila_delgado12 points·1 year ago·edited

Agreed — and the exposure lag means the first fortnight tells you almost nothing.

Adding the one process step — write down where you are before you change anything.

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u/ahmed_okafor4 points·1 year ago

Same. A quiet fortnight after stopping tells you very little; the interesting part starts later.

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u/cormac_roos28 points·1 year ago

That reads as advice to stop, which is not something anyone here should be offering.

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u/marta_weiss51 points·1 year ago

With a week-long half-life, exposure declines over several weeks after the last dose rather than stopping with it. The lag is why the first fortnight is uninformative.

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u/cormac_roos42 points·1 year ago

I would not treat appetite returning as a sign of doing it wrong. It is the expected sequence.

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u/viktor_kirchner-33 points·1 year ago

What are you planning to watch for, and over what period?

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u/micro_bump_mick1 point·1 year ago

Interval stretching lowers the trough concentration while keeping the dose; dose reduction lowers the level while keeping the rhythm. They are different interventions with different subjective profiles.

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u/skip_week_scepticMOD1 point·1 year ago

Left up. It is honest about the reason for stopping and about the timeline.

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u/maintenance_mode_maxmaintenance1 point·1 year ago

coming back later is allowed and it is common

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u/ignacio_silva21 points·1 year ago·edited

Disagree with the framing. Regain is the documented outcome after discontinuation; calling it a personal failure is both wrong and corrosive.

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About c/tapering

Stopping on purpose: dose reduction versus interval stretching, what the discontinuation arms of STEP 1 and SURMOUNT-4 actually showed about regain, appetite return timelines, and the people who came off, regained, and went back on without treating it as a failure.

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