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c/tapering·posted 1 year ago by u/maren_baptista

switched from 5mg to 10mg and nausea got better, not worse

Results Receipts ×4

switched from 5mg to 10mg and nausea got better, not worse. Making the case below, and I expect to lose some of it in the comments.

Pulling the figures out of the title: 5mg and 10mg. All of it is written down as it happened rather than reconstructed.

Stopped abruptly once and gradually once. The gradual one was easier to interpret because I could see what was changing.

Had the conversation with a clinician before stopping rather than after. Considerably easier that way round.

Not medical advice, obviously, and nothing here is approved for human use. One person with a spreadsheet.

729 up / 279 down72% upvoted12 commentsid fn7v0j29 Mar 2025

12 comments

7 in this archive, depth 3

best — the order this archive was captured in

u/anders_kuusela89 points·1 year ago

A written baseline — dose, date, weight, waist, and how appetite feels — taken before any change is what makes the following months interpretable rather than a series of impressions.

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u/vikram_asante44 points·1 year ago

There is very little published guidance on stopping specifically, which is exactly why board consensus here should carry less weight than usual and a clinician conversation should carry more.

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u/maren_baptistaOP28 points·1 year ago

There is very little published guidance on stopping specifically, which is exactly why board consensus here should carry less weight than usual and a

Adding the one process step — write down where you are before you change anything.

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u/maren_baptistaOP130 points·1 year ago

Stretched from seven days to ten to twelve over four months. Appetite told me where the limit was each time.

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u/adaeze_weiss174 points·1 year ago

Stretched from seven days to ten to twelve over four months.

Disagreeing with this bit: stretching and reducing are different things and the post treats them as one.

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u/viktor_laurent55 points·1 year ago·edited

Withdrawal studies across this class consistently show substantial regain after discontinuation, with appetite typically returning before weight changes. That is a description of the pharmacology of a chronic condition.

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u/marta_weiss80 points·1 year ago

Nothing on this board is a taper schedule, and no member can write one for another. What can be shared is what people watched and what they observed.

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About c/tapering

Stopping on purpose: dose reduction versus interval stretching, what the discontinuation arms of STEP 1 and SURMOUNT-4 actually showed about regain, appetite return timelines, and the people who came off, regained, and went back on without treating it as a failure.

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