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c/tapering·submitted 3 months ago by u/nikhil_lindqvist

regain — my 2-week log, condensed into one table

Questionbranch of 12 comments

The title is the argument: regain — my 2-week log, condensed into one table. Here is the rest of it. Withdrawal studies across this class consistently show substantial regain after discontinuation, with appetite typically returning before weight changes. That is a description of the pharmacology of a chronic…

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12 comments, started 3 months ago
u/priya_weiss-24 points·3 months ago

With a week-long half-life, exposure declines over several weeks after the last dose rather than stopping with it. The lag is why the first fortnight is uninformative.

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u/skip_week_scepticMOD1 point·3 months ago

Left up. It is honest about the reason for stopping and about the timeline.

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u/rekha_teixeira1 point·3 months ago

Not convinced. Two weeks of stable weight is not evidence of anything yet.

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[removed]1 point·3 months ago

[removed by moderator]

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u/nabila_bakken1 point·3 months ago

Yes — the withdrawal literature is consistent and it is a pharmacological finding, not a moral one.

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u/rafael_sjoberg1 point·3 months ago

watch appetite, not the scale, for the first month

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u/rina_bergstrom1 point·3 months ago

Careful — interval stretching and dose reduction are different interventions and your post uses them interchangeably.

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u/vikram_asante1 point·3 months ago

Push back: that is a taper schedule aimed at another member and this board does not host those.

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u/helga_vermeulen1 point·3 months ago

coming back later is allowed and it is common

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u/naomi_ekstrom1 point·3 months ago

stopping is a plan, not an event

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u/nikhil_lindqvistOP1 point·3 months ago

stretching to ten days then twelve is the pattern people report

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u/rafael_sjoberg1 point·3 months ago·edited

stretching to ten days then twelve is the pattern people report

This is the sentence that reframes the whole board. Appetite first, scale later.

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About c/tapering

Stopping on purpose: dose reduction versus interval stretching, what the discontinuation arms of STEP 1 and SURMOUNT-4 actually showed about regain, appetite return timelines, and the people who came off, regained, and went back on without treating it as a failure.

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