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c/tapering·submitted 4 months ago by u/chidi_vermeulen

13 months in and discontinuation is still the thing I get wrong

Regainbranch of 9 comments

Check-in as promised in the title: 13 months in and discontinuation is still the thing I get wrong. The relevant figures are 13 months, and they come from the same log I have kept the whole time. Had the conversation with a clinician before stopping rather than after. Considerably easier that way round. Stopped…

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This branch

9 comments, started 4 months ago
u/neha_krastev29 points·4 months ago·edited

Withdrawal studies across this class consistently show substantial regain after discontinuation, with appetite typically returning before weight changes. That is a description of the pharmacology of a chronic condition.

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u/zeynep_villalobos18 points·4 months ago

have the conversation with a clinician before, not after

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u/chidi_vermeulenOP12 points·4 months ago

The habits are what carried it for a while. When they slipped, everything else followed, in that order.

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u/dario_stanescu8 points·4 months ago

Careful — interval stretching and dose reduction are different interventions and your post uses them interchangeably.

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u/rina_bergstrom3 points·4 months ago

Careful — interval stretching and dose reduction are different interventions and your post uses them interchangeably.

This is the sentence that reframes the whole board. Appetite first, scale later.

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u/fabio_lehtinen2 points·4 months ago·edited

Push back: that is a taper schedule aimed at another member and this board does not host those.

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u/elin_varga10 points·4 months ago

Small fix — you have described interval stretching and called it a taper. The exposure profiles differ.

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u/appeal_letter_al-33 points·4 months ago

I would not treat appetite returning as a sign of doing it wrong. It is the expected sequence.

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u/chidi_vermeulenOP1 point·4 months ago

Stretching the interval or reducing the dose?

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About c/tapering

Stopping on purpose: dose reduction versus interval stretching, what the discontinuation arms of STEP 1 and SURMOUNT-4 actually showed about regain, appetite return timelines, and the people who came off, regained, and went back on without treating it as a failure.

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