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c/tapering·posted 5 months ago by u/neha_mwangi

am I the only one who found interval stretching harder than the injections

Question Clean Column ×1

Trying to get a straight answer on this: am I the only one who found interval stretching harder than the injections.

Regained most of it over a year and spent that year assuming it was my fault. It was not; it is what the literature describes.

Wrote down where I was before changing anything. That single page made the following six months interpretable.

Stretched from seven days to ten to twelve over four months. Appetite told me where the limit was each time.

Ask me anything specific. Anything general I will probably get wrong.

972 up / 173 down85% upvoted44 commentsid 1j1tqi26 Feb 2026

44 comments

18 in this archive, depth 5

best — the order this archive was captured in

u/maintenance_mode_maxMOD202 points·5 months ago

Pointing the clinical part of this at somebody qualified. The experience part can stay here.

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u/source_or_silence281 points·5 months ago·edited

stopping abruptly and stopping gradually are different experiences

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u/neha_mwangiOP-22 points·5 months ago

stopping abruptly and stopping gradually are different experiences

Agreed — and the exposure lag means the first fortnight tells you almost nothing.

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u/aleksi_lehtinen1 point·5 months ago

stopping is a plan, not an event

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[deleted]1 point·5 months ago

[deleted]

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u/yara_bakken98 points·5 months ago·edited

Withdrawal studies across this class consistently show substantial regain after discontinuation, with appetite typically returning before weight changes. That is a description of the pharmacology of a chronic condition.

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u/neha_mwangiOP45 points·5 months ago

Is this a pause or a stop? They are different plans.

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u/meera_oyelaran99 points·5 months ago

This. Decide in advance what you are watching for. Deciding in the middle of it is much harder.

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u/salma_vasquez46 points·5 months ago

What is prompting the decision — cost, supply, side effects, or something else?

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u/osman_eriksen35 points·5 months ago

Stopped for cost reasons. Appetite came back at about week 20, well before the scale moved, exactly as this board said it would.

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u/dario_stanescu23 points·5 months ago

Not convinced. Two weeks of stable weight is not evidence of anything yet.

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u/neha_mwangiOP9 points·5 months ago

Had the conversation with a clinician before stopping rather than after. Considerably easier that way round.

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u/zeynep_weiss7 points·5 months ago

stretching to ten days then twelve is the pattern people report

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u/hana_lehtinen28 points·5 months ago

With a week-long half-life, exposure declines over several weeks after the last dose rather than stopping with it. The lag is why the first fortnight is uninformative.

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u/quiet_reader_9914 points·5 months ago·edited

What are you planning to watch for, and over what period?

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u/vial_math_verasyringe math19 points·5 months ago

There is very little published guidance on stopping specifically, which is exactly why board consensus here should carry less weight than usual and a clinician conversation should carry more.

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u/farid_kuipers8 points·5 months ago

decide what you are watching for before you stop

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u/appeal_letter_al6 points·5 months ago

write down where you are before you change anything

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About c/tapering

Stopping on purpose: dose reduction versus interval stretching, what the discontinuation arms of STEP 1 and SURMOUNT-4 actually showed about regain, appetite return timelines, and the people who came off, regained, and went back on without treating it as a failure.

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