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c/tapering·posted 1 months ago by u/coa_janitor

how much of what we believe about interval stretching actually comes from tapering threads

Regain Receipts ×6

Asking properly rather than in a comment on somebody else’s thread: how much of what we believe about interval stretching actually comes from tapering threads.

A written baseline — dose, date, weight, waist, and how appetite feels — taken before any change is what makes the following months interpretable rather than a series of impressions.

Stopped for cost reasons. Appetite came back at about week 3, well before the scale moved, exactly as this board said it would.

With a week-long half-life, exposure declines over several weeks after the last dose rather than stopping with it. The lag is why the first fortnight is uninformative.

Sceptical readings welcome. The confident ones are the ones I distrust.

514 up / 53 down91% upvoted25 commentsid 1ds4fu27 Jun 2026

25 comments

20 in this archive, depth 4

best — the order this archive was captured in

u/naomi_ekstrom96 points·1 months ago·edited

There is very little published guidance on stopping specifically, which is exactly why board consensus here should carry less weight than usual and a clinician conversation should carry more.

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u/nora_ramos22 points·1 months ago

There is very little published guidance on stopping specifically, which is exactly why board consensus here should carry less weight than usual and a

Disagreeing with this bit: stretching and reducing are different things and the post treats them as one.

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u/preservative_free_p54 points·1 months ago

Appetite is the proximal effect and weight is the lagging integrated outcome, which is why watching appetite gives you an earlier and more honest signal.

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u/taper_off_tabithaMOD33 points·1 months ago

Edited a comment framing regain as a moral failure. The documented outcome is not a character verdict.

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u/ahmed_cardoso22 points·1 months ago

Withdrawal studies across this class consistently show substantial regain after discontinuation, with appetite typically returning before weight changes. That is a description of the pharmacology of a chronic condition.

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u/coa_janitorOPmod · c/coa13 points·1 months ago·edited

Have you had the conversation with a clinician yet?

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u/yara_bakken20 points·1 months ago

stopping is a plan, not an event

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u/ilias_kaufmann11 points·1 months ago

Yes — the withdrawal literature is consistent and it is a pharmacological finding, not a moral one.

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[removed]10 points·1 months ago

[removed by moderator]

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u/osman_eriksen6 points·1 months ago·edited

How long were you at the dose you are coming off?

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u/taper_off_tabitha16 points·1 months ago·edited

Interval stretching lowers the trough concentration while keeping the dose; dose reduction lowers the level while keeping the rhythm. They are different interventions with different subjective profiles.

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u/yara_bakken4 points·1 months ago·edited

Agreed. Appetite is the leading indicator and the scale is the lagging one. Watch the first, not the second.

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u/ilias_kaufmann1 point·1 months ago

Agreed.

yara_bakken is right that regain is a documented outcome rather than a character verdict.

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u/marisol_kravchenko2 points·1 months ago·edited

Agreed.

Adding the one process step — write down where you are before you change anything.

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u/coa_janitorOPmod · c/coa0 points·1 months ago

What are you planning to watch for, and over what period?

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u/cormac_roos1 point·1 months ago

Nothing on this board is a taper schedule, and no member can write one for another. What can be shared is what people watched and what they observed.

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u/ismael_varga1 point·1 months ago·edited

interval stretching is the most commonly described approach here

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u/laila_delgado1 point·1 months ago

regain is the expected outcome and framing it as failure helps nobody

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u/zeynep_ndiaye11 points·1 months ago·edited

appetite comes back before the weight does

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About c/tapering

Stopping on purpose: dose reduction versus interval stretching, what the discontinuation arms of STEP 1 and SURMOUNT-4 actually showed about regain, appetite return timelines, and the people who came off, regained, and went back on without treating it as a failure.

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